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Hunter C, Blake H, Jeyadevan N, et al. Local staging and assessment of colon cancer with 1.5-T magnetic resonance imaging. Br J Radiol. 2016;89(1064):20160257doi: 10.1259/bjr.20160257.
Hunter, C., Blake, H., Jeyadevan, N., Abulafi, M., Swift, I., Toomey, P., & Brown, G. (2016). Local staging and assessment of colon cancer with 1.5-T magnetic resonance imaging. The British journal of radiology, 89(1064), 20160257. https://doi.org/10.1259/bjr.20160257
Hunter, Chris, et al. "Local staging and assessment of colon cancer with 1.5-T magnetic resonance imaging." The British journal of radiology vol. 89,1064 (2016): 20160257. doi: https://doi.org/10.1259/bjr.20160257
Hunter C, Blake H, Jeyadevan N, Abulafi M, Swift I, Toomey P, Brown G. Local staging and assessment of colon cancer with 1.5-T magnetic resonance imaging. Br J Radiol. 2016 Aug;89(1064):20160257. doi: 10.1259/bjr.20160257. Epub 2016 May 26. PMID: 27226219; PMCID: PMC5124895.
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Br J Radiol. 2016 Aug;89(1064):20160257. doi: 10.1259/bjr.20160257. Epub 2016 May 26.

Local staging and assessment of colon cancer with 1.5-T magnetic resonance imaging.

The British journal of radiology

Chris Hunter, Helena Blake, Nelesh Jeyadevan, Muti Abulafi, Ian Swift, Paul Toomey, Gina Brown

Affiliations

  1. 1 Department of Surgery and Cancer, Imperial College, London, UK.
  2. 2 Department of Gastrointestinal Radiology, Croydon University Hospital, London, UK.
  3. 3 Department of Colorectal Surgery, Croydon University Hospital, London, UK.
  4. 4 Department of Colorectal Surgery, Epsom and St Helier University Hospitals, London, UK.
  5. 5 Department of Gastrointestinal Radiology, The Royal Marsden Hospital, London, UK.

PMID: 27226219 PMCID: PMC5124895 DOI: 10.1259/bjr.20160257

Abstract

OBJECTIVE:: The aim of this study was to assess the accuracy of 1.5-T MRI in the pre-operative local T and N staging of colon cancer and identification of extramural vascular invasion (EMVI).

METHODS:: Between 2010 and 2012, 60 patients with adenocarcinoma of the colon were prospectively recruited at 2 centres. 55 patients were included for final analysis. Patients received pre-operative 1.5-T MRI with high-resolution T

RESULTS:: Results are reported for two readers. Identification of T3 disease demonstrated an accuracy of 71% and 51%, sensitivity of 74% and 42% and specificity of 74% and 83%. Identification of N1 disease demonstrated an accuracy of 57% for both readers, sensitivity of 26% and 35% and specificity of 81% and 74%. Identification of EMVI demonstrated an accuracy of 74% and 69%, sensitivity 63% and 26% and specificity 80% and 91%.

CONCLUSION:: 1.5-T MRI achieved a moderate accuracy in the local evaluation of colon cancer, but cannot be recommended to replace CT on the basis of this study.

ADVANCES IN KNOWLEDGE:: This study confirms that MRI is a viable alternative to CT for the local assessment of colon cancer, but this study does not reproduce the very high accuracy reported in the only other study to assess the accuracy of MRI in colon cancer staging.

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