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Kumar MS, Gannepalli A, Chandragiri A, et al. Diffuse Large B-Cell Lymphoma of Maxilla - A Case Report of Late Relapse. J Clin Diagn Res. 2016;10(4):ZD12-4doi: 10.7860/JCDR/2016/16139.7695.
Kumar, M. S., Gannepalli, A., Chandragiri, A., & Amarnath, K. (2016). Diffuse Large B-Cell Lymphoma of Maxilla - A Case Report of Late Relapse. Journal of clinical and diagnostic research : JCDR, 10(4), ZD12-4. https://doi.org/10.7860/JCDR/2016/16139.7695
Kumar, Medikonda Suresh, et al. "Diffuse Large B-Cell Lymphoma of Maxilla - A Case Report of Late Relapse." Journal of clinical and diagnostic research : JCDR vol. 10,4 (2016): ZD12-4. doi: https://doi.org/10.7860/JCDR/2016/16139.7695
Kumar MS, Gannepalli A, Chandragiri A, Amarnath K. Diffuse Large B-Cell Lymphoma of Maxilla - A Case Report of Late Relapse. J Clin Diagn Res. 2016 Apr;10(4):ZD12-4. doi: 10.7860/JCDR/2016/16139.7695. Epub 2016 Apr 01. PMID: 27190967; PMCID: PMC4866265.
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J Clin Diagn Res. 2016 Apr;10(4):ZD12-4. doi: 10.7860/JCDR/2016/16139.7695. Epub 2016 Apr 01.

Diffuse Large B-Cell Lymphoma of Maxilla - A Case Report of Late Relapse.

Journal of clinical and diagnostic research : JCDR

Medikonda Suresh Kumar, Ashalata Gannepalli, Anuradha Chandragiri, Konda Amarnath

Affiliations

  1. Professor and Head of Deparment, Department of Oral and Maxillofacial Surgery, Meghana Institute of Dental Sciences , Nizamabad, Telangana, India .
  2. Professor, Department of Oral Maxillofacial Pathology and Microbiology, Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre , Hyderabad, Telangana, India .
  3. Post-graduate Student, Department of Oral Maxillofacial Pathology and Microbiology, Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre , Hyderabad, Telangana, India .
  4. Reader, Department of Oral and Maxillofacial Surgery, Meghana Institute of Dental Sciences , Nizamabad, Telangana, India .

PMID: 27190967 PMCID: PMC4866265 DOI: 10.7860/JCDR/2016/16139.7695

Abstract

Diffuse Large B Cell Lymphomas (DLBCL) encompasses a heterogeneous group of tumors that together constitute the commonest of all Non Hodgkin Lymphoma (NHL) and the proclivity of DLBCL to oral cavity is unknown. They mostly arise from soft tissues as asymptomatic lesions, mostly without 'B' symptoms and involvement of jaw bones is uncommon. Most studies and case reports of oral DLBCL's are based on, manifestation of primary extra-nodal disease or a component of a disseminated disease process involving regional lymph nodes. Many investigators have proposed that patients with this cell type who maintain a complete response for 24 consecutive months are cured because late relapses seldom occur. With advances in treatment modalities, many patients with NHL become long-term survivors and the risk of relapses or second tumors are of growing concern. We present a case of DLBCL which relapsed after five years of initial lesion in a 41 year old female patient and presented as a nonspecific bilateral anterior maxillary radiolucency. DLBCL usually express pan-B markers with small percentage expressing T-cell markers. Few rare cases of DLBCL have shown CD3 expression, which is a most sensitive T-cell marker which was focally expressed in the present case.

Keywords: Immunohistochemistry; Intrabony; Non-Hodgkin’s lymphoma; Radiolucency; Swelling

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