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Pathak R, Bahl G. Asymptomatic Evolution and Regression of Temporal Lobe Necrosis After Adjuvant Radiation for Skin Cancer: A Case Report and Review of Literature. Cureus. 2016;8(2):e481doi: 10.7759/cureus.481.
Pathak, R., & Bahl, G. (2016). Asymptomatic Evolution and Regression of Temporal Lobe Necrosis After Adjuvant Radiation for Skin Cancer: A Case Report and Review of Literature. Cureus, 8(2), e481. https://doi.org/10.7759/cureus.481
Pathak, Rima, and Bahl, Gaurav. "Asymptomatic Evolution and Regression of Temporal Lobe Necrosis After Adjuvant Radiation for Skin Cancer: A Case Report and Review of Literature." Cureus vol. 8,2 (2016): e481. doi: https://doi.org/10.7759/cureus.481
Pathak R, Bahl G. Asymptomatic Evolution and Regression of Temporal Lobe Necrosis After Adjuvant Radiation for Skin Cancer: A Case Report and Review of Literature. Cureus. 2016 Feb 05;8(2):e481. doi: 10.7759/cureus.481. PMID: 27226935; PMCID: PMC4876987.
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Cureus. 2016 Feb 05;8(2):e481. doi: 10.7759/cureus.481.

Asymptomatic Evolution and Regression of Temporal Lobe Necrosis After Adjuvant Radiation for Skin Cancer: A Case Report and Review of Literature.

Cureus

Rima Pathak, Gaurav Bahl

Affiliations

  1. Radiation Oncology, University of British Columbia, BC Cancer Agency.
  2. Division of Radiation Oncology and Developmental Radiotherapeutics, University of British Columbia, BC Cancer Agency ; Radiation Oncology, University of British Columbia, BC Cancer Agency.

PMID: 27226935 PMCID: PMC4876987 DOI: 10.7759/cureus.481

Abstract

Temporal Lobe Necrosis (TLN) is not an expected complication of adjuvant radiation therapy (RT) for skin cancers and has become uncommon otherwise in daily practice due to improved RT planning and modern delivery techniques. TLN is a great mimic and can be mistaken for disease recurrence, metastasis to the brain, or high grade primary brain tumor. This case report demonstrates the importance of diagnosing the entity, its natural evolution, and dosimetric correlation with published constraints.​ It emphasizes the importance of thorough clinical examination on follow-up and review of previous radiation plan when encountered with challenging differentials. We also provide a review of clinical presentations, imaging modalities, and management options for patients with suspected TLN.

Keywords: radiation therapy; skin cancer; temporal lobe necrosis

References

  1. Nan Fang Yi Ke Da Xue Xue Bao. 2008 Mar;28(3):320-3 - PubMed
  2. Int J Radiat Oncol Biol Phys. 2002 May 1;53(1):75-85 - PubMed
  3. Semin Radiat Oncol. 2014 Oct;24(4):265-72 - PubMed
  4. Cancer. 2004 Jan 15;100(2):398-404 - PubMed
  5. Radiology. 1999 Dec;213(3):800-7 - PubMed
  6. Radiat Oncol. 2011 Sep 30;6:128 - PubMed
  7. Int J Radiat Oncol Biol Phys. 2006 Jun 1;65(2):499-508 - PubMed
  8. Int J Radiat Oncol Biol Phys. 1998 Jan 1;40(1):35-42 - PubMed
  9. Head Neck Oncol. 2011 Feb 10;3:8 - PubMed
  10. BMC Cancer. 2013 Aug 27;13:397 - PubMed
  11. Radiat Oncol. 2013 Jan 22;8:17 - PubMed
  12. Int J Radiat Oncol Biol Phys. 1991 May 15;21(1):109-22 - PubMed
  13. Int J Radiat Oncol Biol Phys. 1980 Sep;6(9):1215-28 - PubMed
  14. Int J Radiat Oncol Biol Phys. 1981 Feb;7(2):243-52 - PubMed
  15. Cancer Radiother. 2010 Jul;14 (4-5):263-8 - PubMed

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