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Junqueira MV, Borghi-Pangoni FB, Ferreira SB, et al. Evaluation of the methylene blue addition in binary polymeric systems composed by poloxamer 407 and Carbopol 934P using quality by design: rheological, textural, and mucoadhesive analysis. Drug Dev Ind Pharm. 2016;42(12):2009-2019doi: 10.1080/03639045.2016.1188111.
Junqueira, M. V., Borghi-Pangoni, F. B., Ferreira, S. B., & Bruschi, M. L. (2016). Evaluation of the methylene blue addition in binary polymeric systems composed by poloxamer 407 and Carbopol 934P using quality by design: rheological, textural, and mucoadhesive analysis. Drug development and industrial pharmacy, 42(12), 2009-2019. https://doi.org/10.1080/03639045.2016.1188111
Junqueira, Mariana Volpato, et al. "Evaluation of the methylene blue addition in binary polymeric systems composed by poloxamer 407 and Carbopol 934P using quality by design: rheological, textural, and mucoadhesive analysis." Drug development and industrial pharmacy vol. 42,12 (2016): 2009-2019. doi: https://doi.org/10.1080/03639045.2016.1188111
Junqueira MV, Borghi-Pangoni FB, Ferreira SB, Bruschi ML. Evaluation of the methylene blue addition in binary polymeric systems composed by poloxamer 407 and Carbopol 934P using quality by design: rheological, textural, and mucoadhesive analysis. Drug Dev Ind Pharm. 2016 Dec;42(12):2009-2019. doi: 10.1080/03639045.2016.1188111. Epub 2016 Jun 01. PMID: 27161762.
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Drug Dev Ind Pharm. 2016 Dec;42(12):2009-2019. doi: 10.1080/03639045.2016.1188111. Epub 2016 Jun 01.

Evaluation of the methylene blue addition in binary polymeric systems composed by poloxamer 407 and Carbopol 934P using quality by design: rheological, textural, and mucoadhesive analysis.

Drug development and industrial pharmacy

Mariana Volpato Junqueira, Fernanda Belincanta Borghi-Pangoni, Sabrina Barbosa de Souza Ferreira, Marcos Luciano Bruschi

Affiliations

  1. a Department of Pharmacy, Laboratory of Research and Development of Drug Delivery Systems , State University of Maringá, Avenida Colombo , Maringá , PR , Brazil.

PMID: 27161762 DOI: 10.1080/03639045.2016.1188111

Abstract

This study describes the investigation about the physicochemical behavior of methylene blue (Mb) addition to systems containing poloxamer 407 (Polox), Carbopol 934P (Carb), intended to be locally used by photodynamic therapy. A factorial design 2

Keywords: Bioadhesion; compressional analysis; mucoadhesion; photodynamic therapy; rheology; thermoresponsive systems

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