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Prabhu D, Mehanna E, Gargesha M, et al. 3D registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation. Proc SPIE Int Soc Opt Eng. 2016;9788doi: 10.1117/12.2217537.
Prabhu, D., Mehanna, E., Gargesha, M., Wen, D., Brandt, E., van Ditzhuijzen, N. S., Chamie, D., Yamamoto, H., Fujino, Y., Farmazilian, A., Patel, J., Costa, M., Bezerra, H. G., & Wilson, D. L. (2016). 3D registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation. Proceedings of SPIE--the International Society for Optical Engineering, 9788. https://doi.org/10.1117/12.2217537
Prabhu, David, et al. "3D registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation." Proceedings of SPIE--the International Society for Optical Engineering vol. 9788 (2016). doi: https://doi.org/10.1117/12.2217537
Prabhu D, Mehanna E, Gargesha M, Wen D, Brandt E, van Ditzhuijzen NS, Chamie D, Yamamoto H, Fujino Y, Farmazilian A, Patel J, Costa M, Bezerra HG, Wilson DL. 3D registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation. Proc SPIE Int Soc Opt Eng. 2016 Feb 27;9788. doi: 10.1117/12.2217537. Epub 2016 Mar 29. PMID: 27162417; PMCID: PMC4859892.
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Proc SPIE Int Soc Opt Eng. 2016 Feb 27;9788. doi: 10.1117/12.2217537. Epub 2016 Mar 29.

3D registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation.

Proceedings of SPIE--the International Society for Optical Engineering

David Prabhu, Emile Mehanna, Madhusudhana Gargesha, Di Wen, Eric Brandt, Nienke S van Ditzhuijzen, Daniel Chamie, Hirosada Yamamoto, Yusuke Fujino, Ali Farmazilian, Jaymin Patel, Marco Costa, Hiram G Bezerra, David L Wilson

Affiliations

  1. Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106.
  2. Harrington-McLaughlin Heart & Vascular Institute, University Hospitals Case Medical Center.

PMID: 27162417 PMCID: PMC4859892 DOI: 10.1117/12.2217537

Abstract

High resolution, 100 frames/sec intravascular optical coherence tomography (IVOCT) can distinguish plaque types, but further validation is needed, especially for automated plaque characterization. We developed experimental and 3D registration methods, to provide validation of IVOCT pullback volumes using microscopic, brightfield and fluorescent cryo-image volumes, with optional, exactly registered cryo-histology. The innovation was a method to match an IVOCT pull-back images, acquired in the catheter reference frame, to a true 3D cryo-image volume. Briefly, an 11-parameter, polynomial virtual catheter was initialized within the cryo-image volume, and perpendicular images were extracted, mimicking IVOCT image acquisition. Virtual catheter parameters were optimized to maximize cryo and IVOCT lumen overlap. Local minima were possible, but when we started within reasonable ranges, every one of 24 digital phantom cases converged to a good solution with a registration error of only +1.34±2.65μm (signed distance). Registration was applied to 10 ex-vivo cadaver coronary arteries (LADs), resulting in 10 registered cryo and IVOCT volumes yielding a total of 421 registered 2D-image pairs. Image overlays demonstrated high continuity between vascular and plaque features. Bland-Altman analysis comparing cryo and IVOCT lumen area, showed mean and standard deviation of differences as 0.01±0.43 mm

Keywords: 3D image registration; cryo-imaging; histology; intravascular imaging; optical coherence tomography; validation

References

  1. Am J Pathol. 1991 Nov;139(5):1119-29 - PubMed
  2. J Med Imaging (Bellingham). 2015 Jan;2(1):016001 - PubMed
  3. Arterioscler Thromb Vasc Biol. 1997 Oct;17(10):1859-67 - PubMed
  4. J Am Coll Cardiol. 2002 Feb 20;39(4):604-9 - PubMed
  5. Circulation. 2003 Jan 7;107(1):113-9 - PubMed
  6. N Engl J Med. 1997 May 1;336(18):1276-82 - PubMed
  7. Am Heart J. 2006 Oct;152(4):755.e1-4 - PubMed
  8. Arterioscler Thromb Vasc Biol. 2000 May;20(5):1262-75 - PubMed
  9. Am J Cardiol. 2006 Apr 15;97(8):1172-5 - PubMed
  10. Opt Lett. 2014 Oct 15;39(20):5973-6 - PubMed
  11. Circulation. 2011 Jun 28;123(25):2954-63 - PubMed
  12. J Biomed Opt. 2010 Jan-Feb;15(1):011105 - PubMed
  13. J Biomed Opt. 2008 May-Jun;13(3):034003 - PubMed
  14. Biomed Opt Express. 2012 Jun 1;3(6):1413-26 - PubMed
  15. J Am Coll Cardiol. 2006 Apr 18;47(8 Suppl):C13-8 - PubMed
  16. IEEE Trans Inf Technol Biomed. 2008 May;12(3):348-55 - PubMed
  17. Nat Rev Cardiol. 2011 Mar;8(3):131-9 - PubMed
  18. Curr Cardiovasc Imaging Rep. 2011 Aug;4(4):276-283 - PubMed
  19. Biomed Opt Express. 2013 Jun 04;4(7):1014-30 - PubMed
  20. Anat Rec (Hoboken). 2009 Mar;292(3):342-51 - PubMed
  21. Proc SPIE Int Soc Opt Eng. 2006 Jan 1;6143:nihpa112282 - PubMed
  22. JACC Cardiovasc Imaging. 2011 Jul;4(7):810-3 - PubMed
  23. Circ Cardiovasc Imaging. 2011 Mar;4(2):169-78 - PubMed
  24. Circulation. 2002 Sep 24;106(13):1640-5 - PubMed
  25. Histochem Cell Biol. 2000 May;113(5):331-9 - PubMed
  26. Int Heart J. 2011;52(3):175-9 - PubMed
  27. J Am Coll Cardiol. 1985 Feb;5(2 Pt 1):342-6 - PubMed

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