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Turk J Haematol. 2010 Jun 05;27(2):117-9. doi: 10.5152/tjh.2010.10.

An unusual presentation of pediatric acute lymphoblastic leukemia with parotid gland involvement and dactylitis.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Şule Ünal, Barış Kuşkonmaz, Yasemin Işık Balcı, Bülent Cengiz, Murat Tuncer, Aytemiz Gürgey, Erman Cilsal, Ayşe Gültekingil, Fatma Gümrük

Affiliations

  1. Hacettepe University, Division of Pediatric Hematology 06100 Ankara, Türkiye Phone: + 90 312 305 11 70 E-mail: [email protected].

PMID: 27263454 DOI: 10.5152/tjh.2010.10

Abstract

Mumps infection during the course of childhood acute lymphoblastic leukemia (ALL) treatment has been reported to have a mild course and this was related to the intrinsic low cytopathological effect of the virus, contrasting with the severe course of measles and Varicella zoster virus infections in immunocompromised patients. Herein, we present a three-year-old girl, who was previously vaccinated against mumps infection, admitted with bilateral parotid swelling, dactylitis and serum immunoglobulin M positivity for mumps infection and diagnosed to have ALL with bilateral persistent parotid involvement, inconsistent with mumps infection. Acute leukemia should be suspected during the atypical course of any disease during childhood. Besides, mumps infection at presentation of ALL, as similar to infection emerging during the period of the leukemia treatment, has a mild course.

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