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Turk J Haematol. 2004 Mar 05;21(1):45-8.

A Case with Chronic Eosinophilic Leukaemia Resulting in Blastic Transformation.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Abdullah Hacıhanefioğlu, Muharrem Akkaş, Pınar Tarkun, A Turgut Karakaya, Cengiz Erçin

PMID: 27263647

Abstract

Chronic eosinophilic leukaemia is a rare myeloproliferative disease different from the chronic myeloid leukaemia. It is a haematologic malignancy that must be considered separately from other causes of eosinophilia due to its remarkable clonal eosinophilia. Here, we describe a case with chronic eosinophilic leukaemia which was initially hypereosinophilic (eosinophil count: 85.4 x 109/L) and displayed blastic transformation after a 9 months follow up. We suggest the invasion of spleen, probable invasion of the liver and the blastic transformation of this case must be discerned as a different entity rather than the other causes of eosinophilia.

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