Display options
Cite
Iizuka S, Kuroda H, Yoshimura K, et al. Predictors of indocyanine green visualization during fluorescence imaging for segmental plane formation in thoracoscopic anatomical segmentectomy. J Thorac Dis. 2016;8(5):985-91doi: 10.21037/jtd.2016.03.59.
Iizuka, S., Kuroda, H., Yoshimura, K., Dejima, H., Seto, K., Naomi, A., Mizuno, T., Sakakura, N., & Sakao, Y. (2016). Predictors of indocyanine green visualization during fluorescence imaging for segmental plane formation in thoracoscopic anatomical segmentectomy. Journal of thoracic disease, 8(5), 985-91. https://doi.org/10.21037/jtd.2016.03.59
Iizuka, Shuhei, et al. "Predictors of indocyanine green visualization during fluorescence imaging for segmental plane formation in thoracoscopic anatomical segmentectomy." Journal of thoracic disease vol. 8,5 (2016): 985-91. doi: https://doi.org/10.21037/jtd.2016.03.59
Iizuka S, Kuroda H, Yoshimura K, Dejima H, Seto K, Naomi A, Mizuno T, Sakakura N, Sakao Y. Predictors of indocyanine green visualization during fluorescence imaging for segmental plane formation in thoracoscopic anatomical segmentectomy. J Thorac Dis. 2016 May;8(5):985-91. doi: 10.21037/jtd.2016.03.59. PMID: 27162675; PMCID: PMC4842821.
Copy Download .nbib Format: NLM
Share it on

J Thorac Dis. 2016 May;8(5):985-91. doi: 10.21037/jtd.2016.03.59.

Predictors of indocyanine green visualization during fluorescence imaging for segmental plane formation in thoracoscopic anatomical segmentectomy.

Journal of thoracic disease

Shuhei Iizuka, Hiroaki Kuroda, Kenichi Yoshimura, Hitoshi Dejima, Katsutoshi Seto, Akira Naomi, Tetsuya Mizuno, Noriaki Sakakura, Yukinori Sakao

Affiliations

  1. 1 Department of Thoracic surgery, Aichi Cancer Center Hospital, Nagoya, Japan ; 2 Innovative Clinical Research Center, Kanazawa University, Kanazawa, Japan.

PMID: 27162675 PMCID: PMC4842821 DOI: 10.21037/jtd.2016.03.59

Abstract

BACKGROUND: To determine factors predicting indocyanine green (ICG) visualization during fluorescence imaging for segmental plane formation in thoracoscopic anatomical segmentectomy.

METHODS: Intraoperatively, the intravenous ICG fluorescence imaging system during thoracoscopic anatomical segmentectomy obtained fluorescence emitted images of its surfaces during lung segmental plane formation after the administration of 5 mg/body weight of ICG. The subtraction of regularization scale for calculating the exciting peaks of ICG between the planned segments to resect and to remain was defined as ΔIntensity (ΔI). Variables such as the ratio of forced expiratory volume in 1 s to forced vital capacity (%FEV1.0), smoking index (SI), body mass index (BMI), and low attenuation area (LAA) on computed tomography (CT) took a leading part.

RESULTS: The formation of the segmental plane was successfully accomplished in 98.6% segments and/or subsegments. SI and LAA significantly affected ΔI levels. The area under the receiver operating characteristic curve for the %FEV1.0, SI, and LAA was 0.56, 0.70, and 0.74, respectively. SI >800 and LAA >1.0% were strong predictors of unfavorable ICG visibility (P=0.04 and 0.01, respectively).

CONCLUSIONS: Fluorescence imaging with ICG was a safe and effective method for segmental plane formation during thoracoscopic anatomical segmentectomy. In spite of its high success rate, unfavorable visibility may potentially occur in patients who are heavy smokers or those with a LAA (>1.0%) on CT.

Keywords: Indocyanine green (ICG); chronic obstructive pulmonary disease (COPD); fluorescence; segmentectomy; thoracoscopic surgery (TS)

References

  1. Ann Thorac Surg. 2013 Jun;95(6):2188-90 - PubMed
  2. J Thorac Cardiovasc Surg. 2007 Dec;134(6):1498-501 - PubMed
  3. Nat Biotechnol. 2004 Jan;22(1):93-7 - PubMed
  4. Eur J Cardiothorac Surg. 2014 Jul;46(1):112-5 - PubMed
  5. Eur J Cardiothorac Surg. 2013 Dec;44(6):1103-7 - PubMed
  6. J Thorac Cardiovasc Surg. 2007 Mar;133(3):753-8 - PubMed
  7. Ann Intern Med. 1988 Aug 15;109(4):345-6 - PubMed
  8. Nat Methods. 2012 Jul;9(7):671-5 - PubMed
  9. Respirology. 2004 Nov;9(4):458-65 - PubMed
  10. J Thorac Cardiovasc Surg. 2012 Jul;144(1):87-93 - PubMed
  11. J Thorac Cardiovasc Surg. 2010 Oct;140(4):752-6 - PubMed
  12. Am J Respir Crit Care Med. 2007 Sep 15;176(6):532-55 - PubMed
  13. Ann Thorac Surg. 2011 Nov;92(5):1819-23; discussion 1824-5 - PubMed
  14. Eur Respir J. 2006 Sep;28(3):523-32 - PubMed

Publication Types