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Ocul Oncol Pathol. 2015 Feb;1(2):71-6. doi: 10.1159/000368247. Epub 2014 Oct 22.

Conjunctival Angioimmunoblastic T-Cell Lymphoma.

Ocular oncology and pathology

Darshak S Patel, Paul Rundle, Sachin M Salvi, Malee Fernando, Hardeep Singh Mudhar

Affiliations

  1. Sheffield Ocular Oncology Centre, Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, UK.
  2. Department of Histopathology, Department of Histopathology, Royal Hallamshire Hospital, Sheffield, UK.
  3. National Specialist Ophthalmic Pathology Service (NSOPS), Department of Histopathology, Royal Hallamshire Hospital, Sheffield, UK.

PMID: 27231687 PMCID: PMC4873707 DOI: 10.1159/000368247

Abstract

Angioimmunoblastic T-cell lymphoma (AITL) represents an uncommon variant of T-cell lymphomas and most often presents insidiously with systemic symptoms. This report constitutes the first documented case of conjunctival AITL, masquerading as nodular episcleritis, and describes both the clinical and pathological findings. Furthermore, conjunctival T-cell lymphoma in general remains a rare occurrence, and a survey of previously reported cases reveals a wide variation in clinical presentation. A high index of suspicion, thorough examination and conjunctival biopsy are essential to reaching the diagnosis of conjunctival lymphoma.

Keywords: Angioimmunoblastic T-cell lymphoma; Conjunctiva; Differential diagnosis; Epstein-Barr virus; Nodular episcleritis

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