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Proc SPIE Int Soc Opt Eng. 2016 Feb 13;9712. doi: 10.1117/12.2213069. Epub 2016 Mar 14.

Quantitative structural markers of colorectal dysplasia in a cross sectional study of ex vivo murine tissue using label-free multiphoton microscopy.

Proceedings of SPIE--the International Society for Optical Engineering

Sandra P Prieto, Gage J Greening, Keith K Lai, Timothy J Muldoon

Affiliations

  1. Biomedical Engineering Dept., University of Arkansas, Fayetteville, AR 72701.
  2. Dept. of Pathology, University of Arkansas for Medical Sciences, 4301 West Markham St., Little Rock, AR 72205.

PMID: 27134336 PMCID: PMC4847729 DOI: 10.1117/12.2213069

Abstract

Two-photon excitation of label-free tissue is of increasing interest, as advances have been made in endoscopic clinical application of multiphoton microscopy, such as second harmonic generation (SHG) scanning endoscopy used to monitor cervical collagen in mice

Keywords: colorectal cancer; histopathology; image analysis; label-free; mouse model; multiphoton

References

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