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Chu R, Wan LS, Peng XR, et al. Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans. Nat Prod Bioprospect. 2016;6(4):217-23doi: 10.1007/s13659-016-0099-1.
Chu, R., Wan, L. S., Peng, X. R., Yu, M. Y., Zhang, Z. R., Zhou, L., Li, Z. R., & Qiu, M. H. (2016). Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans. Natural products and bioprospecting, 6(4), 217-23. https://doi.org/10.1007/s13659-016-0099-1
Chu, Rui, et al. "Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans." Natural products and bioprospecting vol. 6,4 (2016): 217-23. doi: https://doi.org/10.1007/s13659-016-0099-1
Chu R, Wan LS, Peng XR, Yu MY, Zhang ZR, Zhou L, Li ZR, Qiu MH. Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans. Nat Prod Bioprospect. 2016 Aug;6(4):217-23. doi: 10.1007/s13659-016-0099-1. Epub 2016 May 10. PMID: 27165414; PMCID: PMC4940257.
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Nat Prod Bioprospect. 2016 Aug;6(4):217-23. doi: 10.1007/s13659-016-0099-1. Epub 2016 May 10.

Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans.

Natural products and bioprospecting

Rui Chu, Luo-Sheng Wan, Xing-Rong Peng, Mu-Yuan Yu, Zhi-Run Zhang, Lin Zhou, Zhong-Rong Li, Ming-Hua Qiu

Affiliations

  1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
  2. University of Chinese Academy of Sciences, Beijing, 100049, China.
  3. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China. [email protected].
  4. University of Chinese Academy of Sciences, Beijing, 100049, China. [email protected].

PMID: 27165414 PMCID: PMC4940257 DOI: 10.1007/s13659-016-0099-1

Abstract

Five new ent-kaurane diterpenoids, named mascaroside III-V (1-3), and 20-nor-cofaryloside I-II (4-5), together with seven known diterpenoids, were isolated from methanol extracts of the green coffee beans of Yunnan Arabica Coffee. Their chemical structures were elucidated by extensive spectroscopic analyses. Meanwhile, cytotoxicity assay against HL-60, A-549, SMMC-7721, MCF-7 and SW480 cell lines showed that they have not evident inhibition of cytotoxicity.

Keywords: Coffea arabica L.; Diterpenoids; Green coffee beans; Structural elucidation

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