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Wu Z, Chen W, Nayak KS. Minimum Field Strength Simulator for Proton Density Weighted MRI. PLoS One. 2016;11(5):e0154711doi: 10.1371/journal.pone.0154711.
Wu, Z., Chen, W., & Nayak, K. S. (2016). Minimum Field Strength Simulator for Proton Density Weighted MRI. PloS one, 11(5), e0154711. https://doi.org/10.1371/journal.pone.0154711
Wu, Ziyue, et al. "Minimum Field Strength Simulator for Proton Density Weighted MRI." PloS one vol. 11,5 (2016): e0154711. doi: https://doi.org/10.1371/journal.pone.0154711
Wu Z, Chen W, Nayak KS. Minimum Field Strength Simulator for Proton Density Weighted MRI. PLoS One. 2016 May 02;11(5):e0154711. doi: 10.1371/journal.pone.0154711. eCollection 2016. PMID: 27136334; PMCID: PMC4852924.
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PLoS One. 2016 May 02;11(5):e0154711. doi: 10.1371/journal.pone.0154711. eCollection 2016.

Minimum Field Strength Simulator for Proton Density Weighted MRI.

PloS one

Ziyue Wu, Weiyi Chen, Krishna S Nayak

Affiliations

  1. Ming Hsieh Department of Electrical Engineering, University of Southern California, Los Angeles, California, United States of America.
  2. Department of Biomedical Engineering, University of Southern California, Los Angeles, California, United States of America.

PMID: 27136334 PMCID: PMC4852924 DOI: 10.1371/journal.pone.0154711

Abstract

OBJECTIVE: To develop and evaluate a framework for simulating low-field proton-density weighted MRI acquisitions based on high-field acquisitions, which could be used to predict the minimum B0 field strength requirements for MRI techniques. This framework would be particularly useful in the evaluation of de-noising and constrained reconstruction techniques.

MATERIALS AND METHODS: Given MRI raw data, lower field MRI acquisitions can be simulated based on the signal and noise scaling with field strength. Certain assumptions are imposed for the simulation and their validity is discussed. A validation experiment was performed using a standard resolution phantom imaged at 0.35 T, 1.5 T, 3 T, and 7 T. This framework was then applied to two sample proton-density weighted MRI applications that demonstrated estimation of minimum field strength requirements: real-time upper airway imaging and liver proton-density fat fraction measurement.

RESULTS: The phantom experiment showed good agreement between simulated and measured images. The SNR difference between simulated and measured was ≤ 8% for the 1.5T, 3T, and 7T cases which utilized scanners with the same geometry and from the same vendor. The measured SNR at 0.35T was 1.8- to 2.5-fold less than predicted likely due to unaccounted differences in the RF receive chain. The predicted minimum field strength requirements for the two sample applications were 0.2 T and 0.3 T, respectively.

CONCLUSIONS: Under certain assumptions, low-field MRI acquisitions can be simulated from high-field MRI data. This enables prediction of the minimum field strength requirements for a broad range of MRI techniques.

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