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Boonen AL, Lefebvre C, Lambert M, et al. Hypothyroidism Associated with Myeloid Neoplasia. Acta Clin Belg. 1992;47(6):397-400doi: 10.1080/17843286.1992.11718261.
Boonen, A. L., Lefebvre, C., Lambert, M., Fcrrant, A., Michaux, J. L., & Coche, E. (1992). Hypothyroidism Associated with Myeloid Neoplasia. Acta clinica Belgica, 47(6), 397-400. https://doi.org/10.1080/17843286.1992.11718261
Boonen, A L, et al. "Hypothyroidism Associated with Myeloid Neoplasia." Acta clinica Belgica vol. 47,6 (1992): 397-400. doi: https://doi.org/10.1080/17843286.1992.11718261
Boonen AL, Lefebvre C, Lambert M, Fcrrant A, Michaux JL, Coche E. Hypothyroidism Associated with Myeloid Neoplasia. Acta Clin Belg. 1992 Jan;47(6):397-400. doi: 10.1080/17843286.1992.11718261. PMID: 27238402.
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Acta Clin Belg. 1992 Jan;47(6):397-400. doi: 10.1080/17843286.1992.11718261.

Hypothyroidism Associated with Myeloid Neoplasia.

Acta clinica Belgica

A L Boonen, C Lefebvre, M Lambert, A Fcrrant, J L Michaux, E Coche

Affiliations

  1. a Divisions of General Internal Medicine and Haematology* Saint-Luc University Hospital 10, avenue Hippocrate, B-1200 Brussels.

PMID: 27238402 DOI: 10.1080/17843286.1992.11718261

Abstract

We report 2 cases of hypothyroidism in whom the associated haematological disturbances (macrocytic anaemia in both cases, mild leukopenia and thrombo-penia in one patient) failed to be corrected by thyroid hormone replacement therapy. Further investigations led to the diagnosis of acute myeloid leukaemia (AML) in the first patient and myelodysplasia syndrome (MDS) in the other. The reasons of the delayed diagnosis and the possible mechanisms explaining this rare combination are discussed. The hypothesis of a purely coincidental association seems most likely.

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