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Kavaliauskas P, Maziukas R, Samalavicius NE, et al. Subtotal gastrectomy with conventional D2 lymphadenectomy for carcinoma of the distal gastric portion: A retrospective cohort study on clinical outcomes. Ann Med Surg (Lond). 2016;6:36-41doi: 10.1016/j.amsu.2016.01.023.
Kavaliauskas, P., Maziukas, R., Samalavicius, N. E., Kuliavas, J., & Lunevicius, R. (2016). Subtotal gastrectomy with conventional D2 lymphadenectomy for carcinoma of the distal gastric portion: A retrospective cohort study on clinical outcomes. Annals of medicine and surgery (2012), 636-41. https://doi.org/10.1016/j.amsu.2016.01.023
Kavaliauskas, Povilas, et al. "Subtotal gastrectomy with conventional D2 lymphadenectomy for carcinoma of the distal gastric portion: A retrospective cohort study on clinical outcomes." Annals of medicine and surgery (2012) vol. 6 (2016): 36-41. doi: https://doi.org/10.1016/j.amsu.2016.01.023
Kavaliauskas P, Maziukas R, Samalavicius NE, Kuliavas J, Lunevicius R. Subtotal gastrectomy with conventional D2 lymphadenectomy for carcinoma of the distal gastric portion: A retrospective cohort study on clinical outcomes. Ann Med Surg (Lond). 2016 Jan 20;6:36-41. doi: 10.1016/j.amsu.2016.01.023. eCollection 2016 Mar. PMID: 27141301; PMCID: PMC4840235.
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Ann Med Surg (Lond). 2016 Jan 20;6:36-41. doi: 10.1016/j.amsu.2016.01.023. eCollection 2016 Mar.

Subtotal gastrectomy with conventional D2 lymphadenectomy for carcinoma of the distal gastric portion: A retrospective cohort study on clinical outcomes.

Annals of medicine and surgery (2012)

Povilas Kavaliauskas, Rytis Maziukas, Narimantas Evaldas Samalavicius, Justas Kuliavas, Raimundas Lunevicius

Affiliations

  1. School of Medicine, Vilnius University, 21 M.K.Ciurlionio str., LT-03101, Vilnius, Lithuania.
  2. Clinic of Internal Diseases, Family Medicine and Oncology of Medical Faculty, Vilnius University, National Cancer Institute, 1 Santariskiu Str, LT-08660, Vilnius, Lithuania.
  3. Emergency General Surgery and Major Trauma Centre, General Surgery Department, University of Liverpool, Aintree University Hospital NHS Foundation Trust, Lower Lane, Liverpool, L9 7AL, United Kingdom.

PMID: 27141301 PMCID: PMC4840235 DOI: 10.1016/j.amsu.2016.01.023

Abstract

BACKGROUND: The study was aimed to delineate the postoperative morbidity, mortality and long-term follow-up results after R0 subtotal gastrectomy with D2 lymphadenectomy for invasive non-disseminated adenocarcinoma of the distal gastric portion.

METHODS: Between January 2005 and December 2007, 228 patients with median age at hospitalisation 66.6 ± 11.4 years underwent the above mentioned surgery for histologically proven distal gastric adenocarcinoma.

RESULTS: Postoperative morbidity was documented in 92 (40.4%) of patients within 30 days. An anastomotic leakage was diagnosed in two (0.9%), peritonitis in two (0.9%), anastomositis in five (2.2%), and prolonged ileus in six (2.6%) patients. Nine patients died (3.9%). The overall 1-year survival rate was 83.8%, and the 5-year survival rate was 54.4%. Gender, age, TNM stage, pN, and N ratio were independent factors predicting a long-term prognosis for patients.

CONCLUSIONS: A R0 type distal subtotal gastrectomy with standard D2 lymphadenectomy for a histologically proven invasive adenocarcinoma of the distal gastric portion without distant metastasis offers acceptable postoperative morbidity and mortality, and considerably high overall cumulative 5-year survival rate. The probability of cumulative survival decreases five times when the ratio between metastatic and examined lymph nodes is > 0.25.

Keywords: Distal gastrectomy; Gastric cancer; Long-term survival; Morbidity; Mortality

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