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Arujuna AV, Housden RJ, Ma Y, et al. Novel System for Real-Time Integration of 3-D Echocardiography and Fluoroscopy for Image-Guided Cardiac Interventions: Preclinical Validation and Clinical Feasibility Evaluation. IEEE J Transl Eng Health Med. 2014;2:1900110doi: 10.1109/JTEHM.2014.2303799.
Arujuna, A. V., Housden, R. J., Ma, Y., Rajani, R., Gao, G., Nijhof, N., Cathier, P., Bullens, R., Gijsbers, G., Parish, V., Kapetanakis, S., Hancock, J., Rinaldi, C. A., Cooklin, M., Gill, J., Thomas, M., O'neill, M. D., Razavi, R., & Rhode, K. S. (2014). Novel System for Real-Time Integration of 3-D Echocardiography and Fluoroscopy for Image-Guided Cardiac Interventions: Preclinical Validation and Clinical Feasibility Evaluation. IEEE journal of translational engineering in health and medicine, 21900110. https://doi.org/10.1109/JTEHM.2014.2303799
Arujuna, Aruna V, et al. "Novel System for Real-Time Integration of 3-D Echocardiography and Fluoroscopy for Image-Guided Cardiac Interventions: Preclinical Validation and Clinical Feasibility Evaluation." IEEE journal of translational engineering in health and medicine vol. 2 (2014): 1900110. doi: https://doi.org/10.1109/JTEHM.2014.2303799
Arujuna AV, Housden RJ, Ma Y, Rajani R, Gao G, Nijhof N, Cathier P, Bullens R, Gijsbers G, Parish V, Kapetanakis S, Hancock J, Rinaldi CA, Cooklin M, Gill J, Thomas M, O'neill MD, Razavi R, Rhode KS. Novel System for Real-Time Integration of 3-D Echocardiography and Fluoroscopy for Image-Guided Cardiac Interventions: Preclinical Validation and Clinical Feasibility Evaluation. IEEE J Transl Eng Health Med. 2014 Jan 30;2:1900110. doi: 10.1109/JTEHM.2014.2303799. eCollection 2014. PMID: 27170872; PMCID: PMC4852540.
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IEEE J Transl Eng Health Med. 2014 Jan 30;2:1900110. doi: 10.1109/JTEHM.2014.2303799. eCollection 2014.

Novel System for Real-Time Integration of 3-D Echocardiography and Fluoroscopy for Image-Guided Cardiac Interventions: Preclinical Validation and Clinical Feasibility Evaluation.

IEEE journal of translational engineering in health and medicine

Aruna V Arujuna, R James Housden, Yingliang Ma, Ronak Rajani, Gang Gao, Niels Nijhof, Pascal Cathier, Roland Bullens, Geert Gijsbers, Victoria Parish, Stamatis Kapetanakis, Jane Hancock, C Aldo Rinaldi, Michael Cooklin, Jaswinder Gill, Martyn Thomas, Mark D O'neill, Reza Razavi, Kawal S Rhode

Affiliations

  1. King's College LondonDivision of Imaging Sciences and Biomedical EngineeringLondonU.K.SE1 7EH; Guy's and St. Thomas' NHS Foundation TrustDepartment of CardiologyLondonU.K.SE1 7EH.
  2. King's College London Division of Imaging Sciences and Biomedical Engineering London U.K. SE1 7EH.
  3. Guy's and St. Thomas' NHS Foundation Trust Department of Cardiology London U.K. SE1 7EH.
  4. Interventional X-Ray Philips Healthcare Best The Netherlands DA 5680.

PMID: 27170872 PMCID: PMC4852540 DOI: 10.1109/JTEHM.2014.2303799

Abstract

Real-time imaging is required to guide minimally invasive catheter-based cardiac interventions. While transesophageal echocardiography allows for high-quality visualization of cardiac anatomy, X-ray fluoroscopy provides excellent visualization of devices. We have developed a novel image fusion system that allows real-time integration of 3-D echocardiography and the X-ray fluoroscopy. The system was validated in the following two stages: 1) preclinical to determine function and validate accuracy; and 2) in the clinical setting to assess clinical workflow feasibility and determine overall system accuracy. In the preclinical phase, the system was assessed using both phantom and porcine experimental studies. Median 2-D projection errors of 4.5 and 3.3 mm were found for the phantom and porcine studies, respectively. The clinical phase focused on extending the use of the system to interventions in patients undergoing either atrial fibrillation catheter ablation (CA) or transcatheter aortic valve implantation (TAVI). Eleven patients were studied with nine in the CA group and two in the TAVI group. Successful real-time view synchronization was achieved in all cases with a calculated median distance error of 2.2 mm in the CA group and 3.4 mm in the TAVI group. A standard clinical workflow was established using the image fusion system. These pilot data confirm the technical feasibility of accurate real-time echo-fluoroscopic image overlay in clinical practice, which may be a useful adjunct for real-time guidance during interventional cardiac procedures.

Keywords: 3D ultrasound; Cardiac interventional guidance; X-ray fluoroscopy; clinical evaluation; image fusion

References

  1. Med Image Anal. 2012 Jan;16(1):38-49 - PubMed
  2. Med Image Anal. 2005 Apr;9(2):163-75 - PubMed
  3. Phys Med Biol. 2010 Jul 7;55(13):N371-82 - PubMed
  4. J Cardiovasc Electrophysiol. 2007 Apr;18(4):409-14 - PubMed
  5. Circ Cardiovasc Interv. 2010 Dec;3(6):585-92 - PubMed
  6. Pacing Clin Electrophysiol. 2008 Mar;31(3):273-82 - PubMed
  7. J Magn Reson Imaging. 2005 Aug;22(2):291-301 - PubMed
  8. Heart. 2009 Nov;95(22):1881-90 - PubMed
  9. Magn Reson Imaging Clin N Am. 2012 Feb;20(1):117-28 - PubMed
  10. IEEE Trans Med Imaging. 2005 Nov;24(11):1512-24 - PubMed
  11. Med Image Anal. 2009 Jun;13(3):419-31 - PubMed
  12. Am J Cardiol. 2009 Apr 1;103(7):1025-8 - PubMed
  13. Eur Heart J. 2006 May;27(10):1223-9 - PubMed
  14. Circulation. 2009 Feb 3;119(4):587-96 - PubMed
  15. Circ Cardiovasc Imaging. 2008 Jul;1(1):85-6 - PubMed
  16. IEEE Trans Med Imaging. 2003 Nov;22(11):1369-78 - PubMed
  17. J Am Soc Echocardiogr. 2009 Mar;22(3):213-31; quiz 316-7 - PubMed
  18. Int J Comput Assist Radiol Surg. 2012 Jan;7(1):13-25 - PubMed
  19. IEEE Trans Biomed Eng. 2012 May;59(5):1444-53 - PubMed
  20. Lancet. 2003 Dec 6;362(9399):1877-82 - PubMed
  21. Circulation. 1998 Oct 13;98(15):1534-40 - PubMed
  22. Int J Epidemiol. 2000 Jun;29(3):424-8 - PubMed
  23. Circulation. 2007 May 29;115(21):2705-14 - PubMed
  24. Conf Proc IEEE Eng Med Biol Soc. 2010;2010:2313-6 - PubMed

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