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Hashemi H, Beiranvand A, Khabazkhoob M, et al. Corneal elevation and keratoconus indices in a 40- to 64-year-old population, Shahroud Eye Study. J Curr Ophthalmol. 2016;27(3):92-8doi: 10.1016/j.joco.2015.10.007.
Hashemi, H., Beiranvand, A., Khabazkhoob, M., Mehravaran, S., Emamian, M. H., Yekta, A., Shariati, M., & Fotouhi, A. (2015). Corneal elevation and keratoconus indices in a 40- to 64-year-old population, Shahroud Eye Study. Journal of current ophthalmology, 27(3), 92-8. https://doi.org/10.1016/j.joco.2015.10.007
Hashemi, Hassan, et al. "Corneal elevation and keratoconus indices in a 40- to 64-year-old population, Shahroud Eye Study." Journal of current ophthalmology vol. 27,3 (2015): 92-8. doi: https://doi.org/10.1016/j.joco.2015.10.007
Hashemi H, Beiranvand A, Khabazkhoob M, Mehravaran S, Emamian MH, Yekta A, Shariati M, Fotouhi A. Corneal elevation and keratoconus indices in a 40- to 64-year-old population, Shahroud Eye Study. J Curr Ophthalmol. 2016 Jan 05;27(3):92-8. doi: 10.1016/j.joco.2015.10.007. eCollection 2015. PMID: 27239585; PMCID: PMC4881190.
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J Curr Ophthalmol. 2016 Jan 05;27(3):92-8. doi: 10.1016/j.joco.2015.10.007. eCollection 2015.

Corneal elevation and keratoconus indices in a 40- to 64-year-old population, Shahroud Eye Study.

Journal of current ophthalmology

Hassan Hashemi, Asghar Beiranvand, Mehdi Khabazkhoob, Shiva Mehravaran, Mohammad Hassan Emamian, Abbasali Yekta, Mohammad Shariati, Akbar Fotouhi

Affiliations

  1. Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran.
  2. Lorestan University of Medical Sciences, Khorramabad, Iran.
  3. Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.
  4. Center for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran.
  5. Department of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
  6. Department of Community Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  7. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Postal Box: 14155-6446, Tehran, Iran.

PMID: 27239585 PMCID: PMC4881190 DOI: 10.1016/j.joco.2015.10.007

Abstract

PURPOSE: To determine the corneal elevation values and keratoconus indices in the 40- to 64-year-old population and their changes with aging.

METHODS: The 6311 invitees of this study were selected through random cluster sampling, and 5190 of them participated in the study (response rate = 82.2%). Here, we analyzed results of Pentacam acquisitions in 4148 respondents. Cases of keratoconus and forme fruste keratoconus (FFKC) were determined using topography and clinical data. Studied variables included keratoconus indices, central corneal thickness readings, maximum elevations on the anterior and posterior surfaces, and elevation values at the thinnest point, anterior steepest point, and posterior steepest point in healthy, FFKC, and keratoconus groups.

RESULTS: In all subjects, the mean maximum elevations were 6.80 ± 5.0 μm and 16.60 ± 7.7 μm on the anterior and posterior corneal surfaces, respectively. Maximum elevation values on the anterior and posterior corneal surfaces showed significant correlations in the keratoconus, FFKC, and healthy groups (P < 0.002). Maximum anterior elevation correlated with age (r = 0.11, P < 0.001), but maximum posterior elevation showed no such correlation (P = 0.476). Keratoconus indices demonstrated significant changes with age (P < 0.001).

CONCLUSION: Anterior elevation values slightly increase with age, and keratoconus indices change as well. Elevation readings and keratoconus indices in the keratoconus group and FFKC cases are higher than the healthy corneas although their values could be compared with other studies on younger participants.

Keywords: Corneal elevation; Pentacam; adult; cross-sectional study; keratoconus

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