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Ocul Oncol Pathol. 2015 Feb;1(2):93-7. doi: 10.1159/000369823. Epub 2015 Jan 09.

The Development of Orange Pigment Overlying Choroidal Metastasis.

Ocular oncology and pathology

Aline Isabel Riechardt, Enken Gundlach, Antonia M Joussen, Gregor D Willerding

Affiliations

  1. Department of Ophthalmology, Charité Universitätsmedizin, Berlin, Germany.
  2. Department of Ophthalmology, Charité Universitätsmedizin, Berlin, Germany; Klinik für Augenheilkunde, DRK Kliniken Westend, Berlin, Germany.

PMID: 27171491 PMCID: PMC4847653 DOI: 10.1159/000369823

Abstract

AIMS: The aim of this study was to correlate the ophthalmoscopic and histopathological findings of orange pigment overlying a choroidal metastasis.

METHODS: This is a single case report with clinical follow-up and histopathological examination.

RESULTS: Histopathology revealed a choroidal metastasis with subretinal CD68-positive macrophages showing autofluorescent deposits in fluorescence microscopy.

CONCLUSION: The development of orange pigment is not pathognomonic for choroidal melanoma but may be seen in other lesions such as carcinoma metastasis.

Keywords: Choroidal melanoma; Choroidal metastasis; Orange pigment

References

  1. Eye (Lond). 1995;9 ( Pt 6):763-71 - PubMed
  2. Exp Eye Res. 1992 Jul;55(1):21-8 - PubMed
  3. Adv Exp Med Biol. 1989;266:109-16; discussion 116-8 - PubMed
  4. Br J Ophthalmol. 1993 Mar;77(3):149-51 - PubMed
  5. Arch Ophthalmol. 1974 May;91(5):359-62 - PubMed
  6. Ophthalmologe. 2000 May;97(5):342-6 - PubMed
  7. Int Ophthalmol. 2009 Aug;29(4):309-13 - PubMed
  8. Retina. 2002 Dec;22(6):810-3 - PubMed
  9. Am J Ophthalmol. 2001 Dec;132(6):943-5 - PubMed
  10. Eye (Lond). 1990;4 ( Pt 2):382-7 - PubMed
  11. Am J Ophthalmol. 2003 Aug;136(2):264-71 - PubMed
  12. Arch Ophthalmol. 1998 Oct;116(10):1396-7 - PubMed
  13. Br J Ophthalmol. 1998 Feb;82(2):159-61 - PubMed
  14. Proteomics. 2012 Aug;12(15-16):2445-54 - PubMed
  15. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1976 Sep-Oct;81(5):871-81 - PubMed
  16. Br J Ophthalmol. 1998 Oct;82(10):1159-61 - PubMed
  17. Ophthalmologe. 2003 Aug;100(8):618-22 - PubMed

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