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J Surg Case Rep. 2016 May 12;2016(5). doi: 10.1093/jscr/rjw084.

Synchronous metastatic squamous cell carcinoma to the colon and cervical lymph nodes from a carcinoma of unknown primary site: A case report.

Journal of surgical case reports

Homare Ito, Yasuyuki Miyakura, Hidenori Tsukui, Daishi Naoi, Makiko Tahara, Mitsuaki Morimoto, Koji Koinuma, Hisanaga Horie, Alan Kawarai Lefor, Naohiro Sata

Affiliations

  1. Department of Surgery, Jichi Medical University, Shimotsuke, Tochigi, Japan [email protected].
  2. Department of Surgery, Saitama Medical Center, Jichi Medical University, Omiya-ku, Saitama-shi, Saitama, Japan.
  3. Department of Surgery, Jichi Medical University, Shimotsuke, Tochigi, Japan.

PMID: 27173884 PMCID: PMC5000582 DOI: 10.1093/jscr/rjw084

Abstract

Metastatic squamous cell carcinoma (SCC) from an unknown primary site to the colon has not been reported previously. A 75-year-old woman presented with a mass in the left submandibular region. Biopsy revealed a Class V lesion, but the histologic type was undetermined. Surgical resection of the left submandibular gland with cervical lymph node dissection was performed. However, SCC was seen in the lymph nodes only, with no tumor in the submandibular gland. Three months after surgery, computed tomography revealed that the preoperatively diagnosed lesion in the transverse colon had grown considerably. A laparoscopic right hemicolectomy was performed. Histological examination showed features of SCC, similar to the findings in the cervical lymph nodes. We report a rare case of synchronous metastatic SCC to the colon and cervical lymph nodes from a carcinoma of unknown primary site.

Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author 2016.

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