Display options
Cite
Takagi Y, Hozumi T, Takemoto Y, et al. Detection of prolonged regional myocardial systolic dysfunction after exercise-induced myocardial ischemia by strain echocardiography with high frame rate tissue Doppler echocardiography. J Echocardiogr. 2011;9(3):90-6doi: 10.1007/s12574-011-0082-0.
Takagi, Y., Hozumi, T., Takemoto, Y., Negishi, K., Hong, Z., Abo, K., Fujioka, K., Nakao, M., Otsuka, R., Sugioka, K., Kobayashi, Y., Yamagishi, H., Yoshiyama, M., & Yoshikawa, J. (2011). Detection of prolonged regional myocardial systolic dysfunction after exercise-induced myocardial ischemia by strain echocardiography with high frame rate tissue Doppler echocardiography. Journal of echocardiography, 9(3), 90-6. https://doi.org/10.1007/s12574-011-0082-0
Takagi, Yasuhiro, et al. "Detection of prolonged regional myocardial systolic dysfunction after exercise-induced myocardial ischemia by strain echocardiography with high frame rate tissue Doppler echocardiography." Journal of echocardiography vol. 9,3 (2011): 90-6. doi: https://doi.org/10.1007/s12574-011-0082-0
Takagi Y, Hozumi T, Takemoto Y, Negishi K, Hong Z, Abo K, Fujioka K, Nakao M, Otsuka R, Sugioka K, Kobayashi Y, Yamagishi H, Yoshiyama M, Yoshikawa J. Detection of prolonged regional myocardial systolic dysfunction after exercise-induced myocardial ischemia by strain echocardiography with high frame rate tissue Doppler echocardiography. J Echocardiogr. 2011 Sep;9(3):90-6. doi: 10.1007/s12574-011-0082-0. Epub 2011 Feb 11. PMID: 27277175.
Copy Download .nbib Format: NLM
Share it on

J Echocardiogr. 2011 Sep;9(3):90-6. doi: 10.1007/s12574-011-0082-0. Epub 2011 Feb 11.

Detection of prolonged regional myocardial systolic dysfunction after exercise-induced myocardial ischemia by strain echocardiography with high frame rate tissue Doppler echocardiography.

Journal of echocardiography

Yasuhiro Takagi, Takeshi Hozumi, Yasuhiko Takemoto, Kazuaki Negishi, Zhu Hong, Kohji Abo, Kazuya Fujioka, Mitsuru Nakao, Ryo Otsuka, Kenichi Sugioka, Yoshiki Kobayashi, Hiroyuki Yamagishi, Minoru Yoshiyama, Junichi Yoshikawa

Affiliations

  1. Department of Internal Medicine and Cardiology, Osaka City University School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.
  2. Department of Internal Medicine and Cardiology, Osaka City University School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan. [email protected].
  3. Central Clinical Laboratory, Osaka City University Medical School, Osaka, Japan.

PMID: 27277175 DOI: 10.1007/s12574-011-0082-0

Abstract

BACKGROUND: Strain echocardiography has enabled quantification of regional myocardial systolic function objectively and is less influenced by tethering effects and cardiac translational artifact than Doppler tissue imaging. Although strain echocardiography has been applied for the detection of inducible ischemia during dobutamine stress, it has not been fully applied to exercise stress echocardiography (ESE) because of technical difficulties. Prolonged myocardial systolic dysfunction after exercise-induced ischemia has been shown previously. Thus, we designed this study to evaluate whether the myocardial strain analysis can detect myocardial ischemia by the assessment of prolonged regional left ventricular (LV) dysfunction in ESE.

METHODS: We performed ESE with myocardial strain imaging system in 20 consecutive patients who had exercise Tl-201 single photon emission computed tomography (SPECT). Myocardial strain curves were obtained at six segments in mid LV walls from the apical approach before and 5 min after ESE. We measured the duration from the R wave in the electrocardiogram to the timing of peak systolic strain corrected by the square root of the RR interval (TPSc). We finally calculated the differences of TPSc (ΔTPSc) before ESE and 5 min after ESE. The results were compared with SPECT as a reference standard.

RESULTS: A receiver operating characteristic curve demonstrated that a ΔTPSc cutoff value of 70 ms had a sensitivity of 80% and a specificity of 84% for the detection of myocardial ischemia.

CONCLUSIONS: Prolonged regional LV systolic dysfunction assessed by ESE with strain analysis was useful for the detection of myocardial ischemia.

Keywords: Ischemic heart disease; Myocardial strain analysis; Stress echocardiography; Tissue Doppler echocardiography

References

  1. Am J Physiol Heart Circ Physiol. 2001 Apr;280(4):H1770-81 - PubMed
  2. JAMA. 1998 Sep 9;280(10 ):913-20 - PubMed
  3. J Am Coll Cardiol. 1991 Mar 1;17(3):666-9 - PubMed
  4. J Am Coll Cardiol. 2003 Nov 5;42(9):1574-83 - PubMed
  5. Circulation. 2002 Jan 29;105(4):539-42 - PubMed
  6. Heart. 2005 Feb;91(2):152-60 - PubMed
  7. J Cardiol. 2010 Jan;55(1):41-8 - PubMed
  8. J Am Soc Echocardiogr. 1998 Nov;11(11):1013-9 - PubMed
  9. J Am Coll Cardiol. 1996 Feb;27(2):330-6 - PubMed
  10. J Am Soc Echocardiogr. 2000 Aug;13(8):731-7 - PubMed
  11. Circulation. 1988 Oct;78(4):994-1007 - PubMed
  12. J Am Soc Echocardiogr. 2002 Jan;15(1):1-12 - PubMed
  13. J Am Coll Cardiol. 1983 Dec;2(6):1085-91 - PubMed
  14. J Am Soc Echocardiogr. 2006 Aug;19(8):1001-11 - PubMed
  15. Eur J Echocardiogr. 2000 Sep;1(3):154-70 - PubMed
  16. Circulation. 2003 Apr 29;107(16):2120-6 - PubMed
  17. J Am Coll Cardiol. 2002 May 1;39(9):1531-7 - PubMed
  18. Am Heart J. 1990 Nov;120(5):1047-57 - PubMed
  19. Circulation. 1994 Sep;90(3):1168-76 - PubMed
  20. Eur Heart J. 2005 Aug;26(16):1625-32 - PubMed
  21. J Am Soc Echocardiogr. 2003 May;16(5):415-23 - PubMed
  22. Am J Cardiol. 1991 Aug 1;68(4):329-34 - PubMed
  23. Eur J Echocardiogr. 2003 Jun;4(2):81-91 - PubMed
  24. Cardiovasc Res. 1987 Oct;21(10):703-16 - PubMed
  25. J Am Soc Echocardiogr. 1999 Dec;12 (12 ):1073-9 - PubMed
  26. Mayo Clin Proc. 1995 Jan;70(1):5-15 - PubMed
  27. Circulation. 2000 Sep 5;102(10):1158-64 - PubMed
  28. J Am Coll Cardiol. 1992 Jan;19(1):74-81 - PubMed

Publication Types