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Iqbal H, Pan Q. Image guided surgery in the management of head and neck cancer. Oral Oncol. 2016;57:32-9doi: 10.1016/j.oraloncology.2016.04.007.
Iqbal, H., & Pan, Q. (2016). Image guided surgery in the management of head and neck cancer. Oral oncology, 5732-9. https://doi.org/10.1016/j.oraloncology.2016.04.007
Iqbal, Hassan, and Pan, Quintin. "Image guided surgery in the management of head and neck cancer." Oral oncology vol. 57 (2016): 32-9. doi: https://doi.org/10.1016/j.oraloncology.2016.04.007
Iqbal H, Pan Q. Image guided surgery in the management of head and neck cancer. Oral Oncol. 2016 Jun;57:32-9. doi: 10.1016/j.oraloncology.2016.04.007. Epub 2016 Apr 25. PMID: 27208842.
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Oral Oncol. 2016 Jun;57:32-9. doi: 10.1016/j.oraloncology.2016.04.007. Epub 2016 Apr 25.

Image guided surgery in the management of head and neck cancer.

Oral oncology

Hassan Iqbal, Quintin Pan

Affiliations

  1. Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center and Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA. Electronic address: [email protected].
  2. Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center and Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA. Electronic address: [email protected].

PMID: 27208842 DOI: 10.1016/j.oraloncology.2016.04.007

Abstract

Complete resection of head and neck tumors relies on palpation and visual inspection. Achieving a negative margin in remote locations in the head and neck region, especially in close proximity to critical structures, is often difficult to achieve. Positive resection margins in head and neck cancer are at high risk to develop recurrent disease and associated with poor prognosis. Near-infrared fluorescence-guided optical imaging is an emerging technology with the potential to move the surgical field forward and facilitate surgeons to visualize tumors in real-time intra-operatively. In this review, our focus is to discuss the recent advances and the potential application of near infrared (NIR) fluorescent-guided surgery in the management of head and neck cancer.

Copyright © 2016 Elsevier Ltd. All rights reserved.

Keywords: Fluorescence molecular imaging; Head and neck neoplasm; Image guided surgery; Near infrared fluorescence; Sentinel lymph node; Squamous cell carcinoma

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