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McGinley M, Morales-Vidal S, Ruland S. Leucine-Rich Glioma Inactivated-1 and Voltage-Gated Potassium Channel Autoimmune Encephalitis Associated with Ischemic Stroke: A Case Report. Front Neurol. 2016;7:68doi: 10.3389/fneur.2016.00068.
McGinley, M., Morales-Vidal, S., & Ruland, S. (2016). Leucine-Rich Glioma Inactivated-1 and Voltage-Gated Potassium Channel Autoimmune Encephalitis Associated with Ischemic Stroke: A Case Report. Frontiers in neurology, 768. https://doi.org/10.3389/fneur.2016.00068
McGinley, Marisa, et al. "Leucine-Rich Glioma Inactivated-1 and Voltage-Gated Potassium Channel Autoimmune Encephalitis Associated with Ischemic Stroke: A Case Report." Frontiers in neurology vol. 7 (2016): 68. doi: https://doi.org/10.3389/fneur.2016.00068
McGinley M, Morales-Vidal S, Ruland S. Leucine-Rich Glioma Inactivated-1 and Voltage-Gated Potassium Channel Autoimmune Encephalitis Associated with Ischemic Stroke: A Case Report. Front Neurol. 2016 May 09;7:68. doi: 10.3389/fneur.2016.00068. eCollection 2016. PMID: 27242653; PMCID: PMC4860679.
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Front Neurol. 2016 May 09;7:68. doi: 10.3389/fneur.2016.00068. eCollection 2016.

Leucine-Rich Glioma Inactivated-1 and Voltage-Gated Potassium Channel Autoimmune Encephalitis Associated with Ischemic Stroke: A Case Report.

Frontiers in neurology

Marisa McGinley, Sarkis Morales-Vidal, Sean Ruland

Affiliations

  1. Department of Neurology, Loyola University Medical Center , Maywood, IL , USA.
  2. Department of Neurology, Florida Hospital Tampa , Tampa, FL , USA.

PMID: 27242653 PMCID: PMC4860679 DOI: 10.3389/fneur.2016.00068

Abstract

Autoimmune encephalitis is associated with a wide variety of antibodies and clinical presentations. Voltage-gated potassium channel (VGKC) antibodies are a cause of autoimmune non-paraneoplastic encephalitis characterized by memory impairment, psychiatric symptoms, and seizures. We present a case of VGKC encephalitis likely preceding an ischemic stroke. Reports of autoimmune encephalitis associated with ischemic stroke are rare. Several hypotheses linking these two disease processes are proposed.

Keywords: autoimmune encephalitis; ischemic stroke; leucine-rich glioma inactivated-1; limbic encephalitis; voltage-gated potassium channel

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