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Sugimoto K, Saguchi T, Saito K, et al. Hemodynamic changes during balloon-occluded transarterial chemoembolization (B-TACE) of hepatocellular carcinoma observed by contrast-enhanced ultrasound. J Med Ultrason (2001). 2013;41(2):209-15doi: 10.1007/s10396-013-0487-7.
Sugimoto, K., Saguchi, T., Saito, K., Imai, Y., & Moriyasu, F. (2014). Hemodynamic changes during balloon-occluded transarterial chemoembolization (B-TACE) of hepatocellular carcinoma observed by contrast-enhanced ultrasound. Journal of medical ultrasonics (2001), 41(2), 209-15. https://doi.org/10.1007/s10396-013-0487-7
Sugimoto, Katsutoshi, et al. "Hemodynamic changes during balloon-occluded transarterial chemoembolization (B-TACE) of hepatocellular carcinoma observed by contrast-enhanced ultrasound." Journal of medical ultrasonics (2001) vol. 41,2 (2014): 209-15. doi: https://doi.org/10.1007/s10396-013-0487-7
Sugimoto K, Saguchi T, Saito K, Imai Y, Moriyasu F. Hemodynamic changes during balloon-occluded transarterial chemoembolization (B-TACE) of hepatocellular carcinoma observed by contrast-enhanced ultrasound. J Med Ultrason (2001). 2014 Apr;41(2):209-15. doi: 10.1007/s10396-013-0487-7. Epub 2013 Aug 29. PMID: 27277775.
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J Med Ultrason (2001). 2014 Apr;41(2):209-15. doi: 10.1007/s10396-013-0487-7. Epub 2013 Aug 29.

Hemodynamic changes during balloon-occluded transarterial chemoembolization (B-TACE) of hepatocellular carcinoma observed by contrast-enhanced ultrasound.

Journal of medical ultrasonics (2001)

Katsutoshi Sugimoto, Toru Saguchi, Kazuhiro Saito, Yasuharu Imai, Fuminori Moriyasu

Affiliations

  1. Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan. [email protected].
  2. Department of Radiology, Tokyo Medical University, Tokyo, Japan.
  3. Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

PMID: 27277775 DOI: 10.1007/s10396-013-0487-7

Abstract

Balloon-occluded transarterial chemoembolization (B-TACE) is able to achieve denser accumulation of Lipiodol emulsion (LE) in hepatocellular carcinoma (HCC) than conventional TACE. However, to maximize the therapeutic effect of B-TACE, it is imperative to understand the hemodynamic changes that occur during arterial occlusion. We here present two patients with HCC in whom the hemodynamic changes during arterial occlusion were depicted and evaluated by contrast-enhanced ultrasound (CEUS). Arterial flow beyond the catheter tip was observed by CEUS even after balloon occlusion. In one patient, a reduction in arterial blood flow in the HCC was observed by CEUS during balloon occlusion of the target area for embolization. After B-TACE, dense LE accumulation in the HCC nodule was confirmed by flat-panel detector CT, indicating an excellent therapeutic effect. In the other patient, no changes in arterial blood flow in the HCC nodule were observed by CEUS during balloon occlusion of the target area for embolization. After B-TACE, intermediate LE accumulation in the HCC nodule was confirmed by flat-panel detector CT, indicating an incomplete therapeutic effect. The findings obtained in the two patients presented here suggest that B-TACE can be performed more effectively and reliably by monitoring blood flow using CEUS.

Keywords: Balloon-occluded transarterial chemoembolization (B-TACE); Contrast media; Hepatocellular carcinoma; Sonazoid; Ultrasound

References

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