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Nakase H, Herfarth H. Cytomegalovirus Colitis, Cytomegalovirus Hepatitis and Systemic Cytomegalovirus Infection: Common Features and Differences. Inflamm Intest Dis. 2016;1(1):15-23doi: 10.1159/000443198.
Nakase, H., & Herfarth, H. (2016). Cytomegalovirus Colitis, Cytomegalovirus Hepatitis and Systemic Cytomegalovirus Infection: Common Features and Differences. Inflammatory intestinal diseases, 1(1), 15-23. https://doi.org/10.1159/000443198
Nakase, Hiroshi, and Herfarth, Hans. "Cytomegalovirus Colitis, Cytomegalovirus Hepatitis and Systemic Cytomegalovirus Infection: Common Features and Differences." Inflammatory intestinal diseases vol. 1,1 (2016): 15-23. doi: https://doi.org/10.1159/000443198
Nakase H, Herfarth H. Cytomegalovirus Colitis, Cytomegalovirus Hepatitis and Systemic Cytomegalovirus Infection: Common Features and Differences. Inflamm Intest Dis. 2016 Apr;1(1):15-23. doi: 10.1159/000443198. Epub 2016 Jan 23. PMID: 27243020; PMCID: PMC4883584.
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Inflamm Intest Dis. 2016 Apr;1(1):15-23. doi: 10.1159/000443198. Epub 2016 Jan 23.

Cytomegalovirus Colitis, Cytomegalovirus Hepatitis and Systemic Cytomegalovirus Infection: Common Features and Differences.

Inflammatory intestinal diseases

Hiroshi Nakase, Hans Herfarth

Affiliations

  1. Department of Gastroenterology and Hepatology, Division of Endoscopy, Kyoto University Hospital, Kyoto, Japan.
  2. Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, N.C., USA.

PMID: 27243020 PMCID: PMC4883584 DOI: 10.1159/000443198

Abstract

Cytomegalovirus (CMV) is a ubiquitous human herpes virus, which, after often asymptomatic primary infection, establishes a lifelong latent infection that can periodically be reactivated in both immunocompetent and immunosuppressed carriers. Whereas the diagnostic approach in case of a suspicion of CMV reactivation is well defined, the indication for antiviral therapy can often only be made in the context of an extent of organ involvement, the immune status, and comorbidities of the patient. This article reviews the epidemiology, diagnosis, and therapy of CMV reactivation with a focus on inflammatory bowel diseases and potentially different diagnostic and therapeutic approaches in Asia and the Western world.

Keywords: Anti-TNF therapy; Antiviral therapy; Cytomegalovirus; Immunosuppression; Inflammatory bowel diseases

References

  1. J Clin Virol. 2014 Mar;59(3):192-4 - PubMed
  2. World J Gastroenterol. 2014 Mar 14;20(10):2695-703 - PubMed
  3. Inflamm Bowel Dis. 2013 Aug;19(9):1951-63 - PubMed
  4. Am J Gastroenterol. 2010 Mar;105(3):501-23; quiz 524 - PubMed
  5. Lancet Infect Dis. 2004 Dec;4(12):725-38 - PubMed
  6. Transplantation. 1992 Jan;53(1):99-102 - PubMed
  7. J Crohns Colitis. 2013 Nov;7(10):803-11 - PubMed
  8. World J Gastroenterol. 2014 Aug 7;20(29):9699-715 - PubMed
  9. JAMA. 1975 Sep 22;233(12):1284-8 - PubMed
  10. Mod Pathol. 1991 Mar;4(2):149-53 - PubMed
  11. Inflamm Bowel Dis. 2010 Sep;16(9):1620-7 - PubMed
  12. Dig Dis Sci. 2006 Jun;51(6):1052-5 - PubMed
  13. Cell. 1997 Oct 3;91(1):119-26 - PubMed
  14. Inflamm Bowel Dis. 2015 Nov;21(11):2718-25 - PubMed
  15. Ann Intern Med. 1993 Nov 1;119(9):924-35 - PubMed
  16. Am J Gastroenterol. 2001 Mar;96(3):773-5 - PubMed
  17. Clin Microbiol Rev. 1998 Jul;11(3):533-54 - PubMed
  18. J Clin Virol. 2008 Nov;43(3):266-71 - PubMed
  19. Inflamm Bowel Dis. 2007 Dec;13(12):1516-21 - PubMed
  20. Am J Gastroenterol. 2011 Nov;106(11):2001-8 - PubMed
  21. Clin Infect Dis. 2002 Apr 15;34(8):1094-7 - PubMed
  22. Am J Pathol. 1990 Mar;136(3):541-8 - PubMed
  23. Gut. 2013 Sep;62(9):1288-94 - PubMed
  24. J Gastroenterol Hepatol. 1999 Oct;14(10):973-6 - PubMed
  25. Clin Infect Dis. 2015 Mar 15;60(6):e20-6 - PubMed
  26. Gastroenterology. 2008 Aug;135(2):400-9 - PubMed
  27. J Clin Virol. 2008 Oct;43(2):180-3 - PubMed
  28. Dig Liver Dis. 2004 Dec;36(12):818-20 - PubMed
  29. Arch Intern Med. 1998 May 11;158(9):957-69 - PubMed
  30. Clin Microbiol Infect. 2010 Jul;16(7):851-4 - PubMed
  31. Am J Med Sci. 1978 Nov-Dec;276(3):325-39 - PubMed
  32. World J Gastroenterol. 2015 Feb 14;21(6):1915-26 - PubMed
  33. Inflamm Bowel Dis. 2012 Jul;18(7):E1396-7 - PubMed
  34. Clin Infect Dis. 2006 Nov 1;43(9):1143-51 - PubMed
  35. Med J Aust. 2014 Nov 17;201(10 ):578-80 - PubMed
  36. Inflamm Bowel Dis. 2006 Sep;12(9):879-84 - PubMed
  37. Gastroenterology. 1977 Jun;72(6):1253-6 - PubMed
  38. Infection. 1987 Jul-Aug;15(4):228-31 - PubMed
  39. Intest Res. 2014 Jan;12(1):5-11 - PubMed
  40. Clin Gastroenterol Hepatol. 2015 May;13(5):949-55 - PubMed
  41. World J Gastroenterol. 2015 Feb 7;21(5):1689-90 - PubMed
  42. Heart Lung. 2005 Jul-Aug;34(4):291-4 - PubMed
  43. Clin Infect Dis. 1997 Jan;24(1):52-6 - PubMed
  44. Gastroenterology. 1996 Aug;111(2):439-44 - PubMed
  45. J Crohns Colitis. 2009 Sep;3(3):141-8 - PubMed
  46. Am J Gastroenterol. 2001 Dec;96(12):3464-5 - PubMed
  47. Am J Gastroenterol. 1987 Dec;82(12):1264-70 - PubMed
  48. Arch Pathol Lab Med. 2001 Aug;125(8):1042-6 - PubMed
  49. J Infect Dis. 1985 Aug;152(2):243-8 - PubMed
  50. J Acquir Immune Defic Syndr. 1991;4 Suppl 1:S29-35 - PubMed
  51. Am J Gastroenterol. 1986 Oct;81(10):944-50 - PubMed
  52. J Crohns Colitis. 2014 Jun;8(6):443-68 - PubMed
  53. Am J Gastroenterol. 2006 Dec;101(12):2857-65 - PubMed
  54. Inflamm Bowel Dis. 2004 May;10(3):245-50 - PubMed
  55. Aliment Pharmacol Ther. 2015 Jul;42(1):127-9 - PubMed
  56. Am J Med. 1961 Feb;30:334-40 - PubMed
  57. Acta Clin Belg. 2001 Nov-Dec;56(6):341-8 - PubMed
  58. Dig Dis Sci. 2010 Apr;55(4):1053-8 - PubMed
  59. J Med Virol. 1992 Nov;38(3):183-90 - PubMed
  60. Transplant Proc. 2005 Sep;37(7):3059-60 - PubMed
  61. Am J Gastroenterol. 2011 Apr;106(4):574-88 - PubMed
  62. Clin Microbiol Rev. 2002 Oct;15(4):680-715 - PubMed
  63. J Infect Dis. 1985 Feb;151(2):344-8 - PubMed
  64. Pediatr Rev. 2012 Apr;33(4):156-63; quiz 163 - PubMed
  65. J Thromb Thrombolysis. 2009 Nov;28(4):496-9 - PubMed
  66. Ann Intern Med. 1990 Oct 15;113(8):589-93 - PubMed
  67. Rev Infect Dis. 1990 Sep-Oct;12 Suppl 7:S701-10 - PubMed
  68. Digestion. 2011;84(1):3-9 - PubMed
  69. Aliment Pharmacol Ther. 2014 Apr;39(7):712-20 - PubMed
  70. Gastroenterology. 1992 Sep;103(3):1022-5 - PubMed
  71. Scand J Infect Dis. 1998;30(6):559-64 - PubMed
  72. Rev Med Virol. 2010 Jul;20(4):202-13 - PubMed
  73. Am J Gastroenterol. 2007 Feb;102(2):331-7 - PubMed
  74. Inflamm Bowel Dis. 2015 Dec;21(12):2833-8 - PubMed
  75. Inflamm Bowel Dis. 2015 Jul;21(7):1580-6 - PubMed
  76. Hepatogastroenterology. 2012 Oct;59(119):2137-41 - PubMed
  77. Transplantation. 2005 Feb 27;79(4):381-6 - PubMed

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