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J Echocardiogr. 2010 Dec;8(4):129-30. doi: 10.1007/s12574-010-0046-9. Epub 2010 Jun 04.

Left ventricular apical aneurysm due to unrecognized sarcoidosis.

Journal of echocardiography

Tomizo Masuno, Kumiko Hirata, Nozomi Wada, Haruka Endo, Kazushi Takemoto, Tsuyoshi Nishiguchi, Ikuko Teraguchi, Naoki Maniwa, Aiko Shimokado, Manabu Kashiwagi, Hiroto Tsujioka, Hideyuki Ikejima, Akio Kuroi, Kohei Ishibashi, Kenichi Komukai, Takashi Tanimoto, Yasushi Ino, Hironori Kitabata, Keizo Kimura, Toshio Imanishi, Takashi Akasaka

Affiliations

  1. Internal Medicine, Division of Cardiovascular Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
  2. Internal Medicine, Division of Cardiovascular Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan. [email protected].

PMID: 27278945 DOI: 10.1007/s12574-010-0046-9

Abstract

A 47-year-old woman was hospitalized for syncope. An electrocardiogram showed complete right bundle branch block and T-wave inversion in leads III, aVF, and V2-4. Cardiac catheterization was performed since the echocardiogram demonstrated the existence of a left ventricular apical aneurysm and apical thrombus. Coronary angiography revealed normal coronary arteries. An endomyocardial biopsied specimen from the right ventricular apical wall demonstrated typical noncaseating granulomas with giant cells. There was no evidence suggesting the involvement of other systemic organs. The patient was diagnosed as having cardiac sarcoidosis. Cardiac sarcoidosis should be considered within a spectrum of diseases that cause left ventricular apical aneurysm.

Keywords: Cardiac sarcoidosis; Left ventricular aneurysm; Left ventricular apical thrombus; Nonsustained ventricular tachycardia

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