Display options
Cite
Rzeszutko Ł, Siudak Z, Tokarek T, et al. Twelve months clinical outcome after bioresorbable vascular scaffold implantation in patients with stable angina and acute coronary syndrome. Data from the Polish National Registry. Postepy Kardiol Interwencyjnej. 2016;12(2):108-15doi: 10.5114/aic.2016.59360.
Rzeszutko, �. �., Siudak, Z., Tokarek, T., Plens, K., Włodarczak, A., Lekston, A., Ochała, A., Gil, R. J., Balak, W., & Dudek, D. (2016). Twelve months clinical outcome after bioresorbable vascular scaffold implantation in patients with stable angina and acute coronary syndrome. Data from the Polish National Registry. Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 12(2), 108-15. https://doi.org/10.5114/aic.2016.59360
Rzeszutko, Łukasz, et al. "Twelve months clinical outcome after bioresorbable vascular scaffold implantation in patients with stable angina and acute coronary syndrome. Data from the Polish National Registry." Postepy w kardiologii interwencyjnej = Advances in interventional cardiology vol. 12,2 (2016): 108-15. doi: https://doi.org/10.5114/aic.2016.59360
Rzeszutko Ł, Siudak Z, Tokarek T, Plens K, Włodarczak A, Lekston A, Ochała A, Gil RJ, Balak W, Dudek D. Twelve months clinical outcome after bioresorbable vascular scaffold implantation in patients with stable angina and acute coronary syndrome. Data from the Polish National Registry. Postepy Kardiol Interwencyjnej. 2016;12(2):108-15. doi: 10.5114/aic.2016.59360. Epub 2016 May 11. PMID: 27279869; PMCID: PMC4882382.
Copy Download .nbib Format: NLM
Share it on

Postepy Kardiol Interwencyjnej. 2016;12(2):108-15. doi: 10.5114/aic.2016.59360. Epub 2016 May 11.

Twelve months clinical outcome after bioresorbable vascular scaffold implantation in patients with stable angina and acute coronary syndrome. Data from the Polish National Registry.

Postepy w kardiologii interwencyjnej = Advances in interventional cardiology

Łukasz Rzeszutko, Zbigniew Siudak, Tomasz Tokarek, Krzysztof Plens, Adrian Włodarczak, Andrzej Lekston, Andrzej Ochała, Robert J Gil, Wojciech Balak, Dariusz Dudek

Affiliations

  1. 2 Department of Cardiology, Institute of Cardiology, Jagiellonian University, Medical College, Krakow, Poland.
  2. Department of Interventional Cardiology, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
  3. Krakow Cardiovascular Research Institute, Krakow, Poland.
  4. Miedziowe Centrum Zdrowia S.A., Lublin, Poland.
  5. 3 Department and Clinical Unit of Cardiology, Silesian Centre for Heart Diseases, Medical University of Silesia, Zabrze, Poland.
  6. 3 Department of Cardiology, Medical University of Silesia, Katowice, Poland.
  7. Invasive Cardiology Clinic, Central Clinical Hospital of the Internal Affairs and Administration Ministry, Warsaw, Poland; Institute of Experimental and Clinical Medicine, Polish Academy of Science, Warsaw, Poland.
  8. 2 Department of Cardiology, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.

PMID: 27279869 PMCID: PMC4882382 DOI: 10.5114/aic.2016.59360

Abstract

INTRODUCTION: There are limited data describing bioresorbable vascular scaffold (BVS) implantation in complex lesions. Only short-term clinical outcomes are available for patients with acute coronary syndrome (ACS).

AIM: To evaluate 12-month clinical outcome, safety and effectiveness of BVS implantation in complex lesions and in stable angina (SA) or ACS.

MATERIAL AND METHODS: Five hundred ninety-one patients with SA/ACS were enrolled between October 2012 and November 2013 in 30 invasive cardiology centres in Poland. At least one BVS implantation during percutaneous coronary intervention (PCI) was the only inclusion criteria. The clinical endpoint was the occurrence of a major adverse cardiovascular event (MACE) (all-cause death, myocardial infarction (MI), clinically driven target lesion revascularisation (TLR) with urgent PCI or target vessel revascularisation (TVR) with urgent coronary artery bypass grafting (CABG)) and device-oriented composite endpoint (DOCE) (cardiac death, urgent target vessel revascularisation with PCI/CABG, target vessel MI) during 12-month follow-up.

RESULTS: After 12 months TLR with urgent PCI was significantly more often reported in patients with diagnosed UA (4.59%; p < 0.02) in comparison with other PCI indications. No significant differences were found in terms of composite MACE endpoint, cumulative MACE (p = 0.09), stent thrombosis (p = 0.2) or restenosis (p = 0.2). There were no significant differences in cumulative MACE and composite MACE endpoint between patients with no/mild versus moderate/severe tortuosity and no/mild versus moderate/severe calcification of the target vessel. No significant difference was found between groups of patients with or without bifurcation of the target vessel. Device-oriented composite endpoint was significantly more often reported in the ACS group (3.2% vs. 0.47%; p < 0.03), most frequently in patients with diagnosed UA (5.5%).

CONCLUSIONS: Bioresorbable vascular scaffold can be successfully and safely used for ACS treatment and in lesions of higher complexity.

Keywords: bifurcation; calcified; complex lesion; stent; tortuosity

References

  1. Lancet. 2016 Feb 6;387(10018):537-44 - PubMed
  2. EuroIntervention. 2015 Jun;11(2):149-56 - PubMed
  3. EuroIntervention. 2015 Apr;10(12):1396-401 - PubMed
  4. Circulation. 2010 Nov 30;122(22):2288-300 - PubMed
  5. Eur Heart J. 2015 Dec 14;36(47):3332-42 - PubMed
  6. Postepy Kardiol Interwencyjnej. 2014;10(4):283-8 - PubMed
  7. JACC Cardiovasc Interv. 2010 Apr;3(4):449-56 - PubMed
  8. JACC Cardiovasc Interv. 2015 Jan;8(1 Pt B):189-97 - PubMed
  9. JACC Cardiovasc Interv. 2015 Nov;8(13):1715-26 - PubMed
  10. Eur Heart J. 2016 Jan 14;37(3):229-40 - PubMed
  11. Int J Cardiol. 2015 Dec 15;201:129-36 - PubMed
  12. Postepy Kardiol Interwencyjnej. 2015;11(1):64-6 - PubMed
  13. Clin Res Cardiol. 2015 Feb;104(2):124-35 - PubMed
  14. Kardiol Pol. 2014;72 (12 ):1394-9 - PubMed
  15. Postepy Kardiol Interwencyjnej. 2014;10(2):128-9 - PubMed
  16. Cardiovasc Revasc Med. 2015 Sep;16(6):340-3 - PubMed
  17. Catheter Cardiovasc Interv. 2015 Jan 1;85(1):E10-5 - PubMed
  18. Postepy Kardiol Interwencyjnej. 2015;11(3):161-9 - PubMed
  19. EuroIntervention. 2015 Feb;10(10):1144-53 - PubMed
  20. JACC Cardiovasc Interv. 2014 Jul;7(7):741-50 - PubMed
  21. JACC Cardiovasc Interv. 2015 May;8(6):770-7 - PubMed
  22. Heart Lung Circ. 2015 Sep;24(9):854-9 - PubMed
  23. Pol Arch Med Wewn. 2014;124(12 ):669-77 - PubMed
  24. Circulation. 2007 May 1;115(17):2344-51 - PubMed

Publication Types