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Akkoc G, Kadayifci EK, Karaaslan A, et al. Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis. Case Rep Infect Dis. 2016;2016:7549252doi: 10.1155/2016/7549252.
Akkoc, G., Kadayifci, E. K., Karaaslan, A., Atici, S., Yakut, N., Ocal Demir, S., Soysal, A., & Bakir, M. (2016). Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis. Case reports in infectious diseases, 20167549252. https://doi.org/10.1155/2016/7549252
Akkoc, Gulsen, et al. "Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis." Case reports in infectious diseases vol. 2016 (2016): 7549252. doi: https://doi.org/10.1155/2016/7549252
Akkoc G, Kadayifci EK, Karaaslan A, Atici S, Yakut N, Ocal Demir S, Soysal A, Bakir M. Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis. Case Rep Infect Dis. 2016;2016:7549252. doi: 10.1155/2016/7549252. Epub 2016 Apr 26. PMID: 27213062; PMCID: PMC4861786.
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Case Rep Infect Dis. 2016;2016:7549252. doi: 10.1155/2016/7549252. Epub 2016 Apr 26.

Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis.

Case reports in infectious diseases

Gulsen Akkoc, Eda Kepenekli Kadayifci, Ayse Karaaslan, Serkan Atici, Nurhayat Yakut, Sevliya Ocal Demir, Ahmet Soysal, Mustafa Bakir

Affiliations

  1. Division of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, 34890 Istanbul, Turkey.

PMID: 27213062 PMCID: PMC4861786 DOI: 10.1155/2016/7549252

Abstract

Epstein-Barr virus (EBV) usually causes mild, asymptomatic, and self-limited infections in children and adults; however, it may occasionally lead to severe conditions such as neurological diseases, malignant diseases, hepatic failure, and myocarditis. Epstein-Barr virus-related neurological disorders include meningitis, encephalitis, and cranial or peripheral neuritis, which are mostly seen in immunocompromised patients. The therapeutic modalities for EBV-related severe organ damage including central nervous system manifestations are still uncertain. Herein, we describe a seven-year-old boy with EBV encephalitis who presented with prolonged fever, exudative pharyngitis, reduced consciousness, and neck stiffness. Cranial magnetic resonance imaging showed contrast enhancement in the bilateral insular cortex and the right hypothalamus. The diagnosis was made by EBV-DNA amplification in both the blood and cerebrospinal fluid samples. He was discharged with acyclovir therapy without any sequelae.

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