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Ogita S, Endo T, Nomura K, et al. Nasal cavity epithelioid hemangioendothelioma invading the anterior skull base. Surg Neurol Int. 2016;7:53doi: 10.4103/2152-7806.181902.
Ogita, S., Endo, T., Nomura, K., Ogawa, T., Watanabe, M., Higashi, K., Katori, Y., & Tominaga, T. (2016). Nasal cavity epithelioid hemangioendothelioma invading the anterior skull base. Surgical neurology international, 753. https://doi.org/10.4103/2152-7806.181902
Ogita, Shogo, et al. "Nasal cavity epithelioid hemangioendothelioma invading the anterior skull base." Surgical neurology international vol. 7 (2016): 53. doi: https://doi.org/10.4103/2152-7806.181902
Ogita S, Endo T, Nomura K, Ogawa T, Watanabe M, Higashi K, Katori Y, Tominaga T. Nasal cavity epithelioid hemangioendothelioma invading the anterior skull base. Surg Neurol Int. 2016 May 06;7:53. doi: 10.4103/2152-7806.181902. eCollection 2016. PMID: 27213107; PMCID: PMC4866062.
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Surg Neurol Int. 2016 May 06;7:53. doi: 10.4103/2152-7806.181902. eCollection 2016.

Nasal cavity epithelioid hemangioendothelioma invading the anterior skull base.

Surgical neurology international

Shogo Ogita, Toshiki Endo, Kazuhiro Nomura, Takenori Ogawa, Mika Watanabe, Kenjiro Higashi, Yukio Katori, Teiji Tominaga

Affiliations

  1. Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
  2. Department of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
  3. Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan.

PMID: 27213107 PMCID: PMC4866062 DOI: 10.4103/2152-7806.181902

Abstract

BACKGROUND: Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor that frequently occurs in soft tissues. Patients suffer from local recurrence and remote metastasis because of its malignant potential. Here, we present a rare case of EHE that originated from nasal cavity and invaded intracranially through the anterior skull base.

CASE DESCRIPTION: This is a 27-year-old woman who presented a local physician with intermittent epistaxis and a facial pain around her nose. Preoperative studies demonstrated that the tumor invaded into anterior skull base and the dura matter. Therefore, we performed combined skull base and transnasal surgery, which achieved complete resection of the tumor. Postoperative course of the patient was uneventful. No recurrence or distant metastasis was observed in the patient for 2 years following the radical resection.

CONCLUSIONS: To date, four cases of EHE in the nasal cavity were reported. This is the first case in which EHE demonstrated invasive potentials with intracranial extension. Radical surgical resection plays an important role for better management of invasive paranasal EHE.

Keywords: Anterior skull base; epithelioid hemangioendothelioma; nasal cavity; vascular tumor

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