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Gastroenterol Rep (Oxf). 2017 May;5(2):161-164. doi: 10.1093/gastro/gow009. Epub 2016 May 30.

Progressive liver failure post acute hepatitis A, over a three-month period, resulting in hepatorenal syndrome and death.

Gastroenterology report

Tarek Turk, Tareq Al Saadi, Bisher Sawaf, Mahmoud Alkhatib, Mhd Ismael Zakaria, Bisher Daaboul

Affiliations

  1. Faculty of Medicine, University of Damascus, Damascus, Syrian Arab Republic [email protected].
  2. Faculty of Medicine, University of Damascus, Damascus, Syrian Arab Republic.
  3. Faculty of Medicine, Syrian Private University, Damascus, Syrian Arab Republic.
  4. Gastroenterology and Hepatology, Medical Care Center, Damascus, Syrian Arab Republic.

PMID: 27247182 PMCID: PMC5421466 DOI: 10.1093/gastro/gow009

Abstract

Hepatitis A is a common viral illness worldwide. It usually results in an acute, self-limiting disease and only rarely leads to fulminant hepatic failure or any other complications. During the period of conflict in Syria, and due to the damages to water infrastructure and poor sanitation, a dramatic increase in hepatitis A virus infection has been documented. Here we report a rare case of a 14-year-old male whose hepatitis A was complicated with hepatorenal syndrome and subacute liver failure. The war condition in Syria impeded transportation of the patient to a nearby country for liver transplantation, contributing to his unfortunate death.

© The Author(s) 2016. Published by Oxford University Press and Sixth Affiliated Hospital of Sun Yat-Sen University.

Keywords: acute liver failure; hepatitis A virus; hepatorenal syndrome

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