Display options
Share it on

Occup Environ Med. 2016 Jul;73(7):487-96. doi: 10.1136/oemed-2016-103550. Epub 2016 May 13.

Can psychosocial work conditions protect against age-related cognitive decline? Results from a systematic review.

Occupational and environmental medicine

Mette Andersen Nexø, Annette Meng, Vilhelm Borg

Affiliations

  1. The National Research Centre for the Working Environment, Copenhagen, Denmark.

PMID: 27178844 PMCID: PMC4941143 DOI: 10.1136/oemed-2016-103550

Abstract

According to the use it or lose it hypothesis, intellectually stimulating activities postpone age-related cognitive decline. A previous systematic review concluded that a high level of mental work demands and job control protected against cognitive decline. However, it did not distinguish between outcomes that were measured as cognitive function at one point in time or as cognitive decline. Our study aimed to systematically review which psychosocial working conditions were prospectively associated with high levels of cognitive function and/or changes in cognitive function over time. Articles were identified by a systematic literature search (MEDLINE, Web of Science (WOS), PsycNET, Occupational Safety and Health (OSH)). We included only studies with longitudinal designs examining the impact of psychosocial work conditions on outcomes defined as cognitive function or changes in cognitive function. Two independent reviewers compared title-abstract screenings, full-text screenings and quality assessment ratings. Eleven studies were included in the final synthesis and showed that high levels of mental work demands, occupational complexity or job control at one point in time were prospectively associated with higher levels of cognitive function in midlife or late life. However, the evidence to clarify whether these psychosocial factors also affected cognitive decline was insufficient, conflicting or weak. It remains speculative whether job control, job demands or occupational complexity can protect against cognitive decline. Future studies using methodological advancements can reveal whether workers gain more cognitive reserve in midlife and late life than the available evidence currently suggests. The public health implications of a previous review should thereby be redefined accordingly.

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

References

  1. Alzheimers Res Ther. 2015 Mar 18;7(1):17 - PubMed
  2. Neurology. 1993 Jan;43(1):13-20 - PubMed
  3. Occup Environ Med. 2009 Jan;66(1):32-7 - PubMed
  4. J Int Neuropsychol Soc. 2012 Jul;18(4):749-56 - PubMed
  5. Ergonomics. 2010 Nov;53(11):1287-301 - PubMed
  6. J Aging Health. 2007 Jun;19(3):397-415 - PubMed
  7. Lancet Neurol. 2012 Nov;11(11):1006-12 - PubMed
  8. J Clin Epidemiol. 2009 Oct;62(10):1006-12 - PubMed
  9. Intelligence. 2012 Jul;40(4):352-361 - PubMed
  10. J Gerontol B Psychol Sci Soc Sci. 2011 May;66(3):287-91 - PubMed
  11. J Gerontol B Psychol Sci Soc Sci. 2014 Mar;69(2):228-36 - PubMed
  12. Psychol Aging. 1999 Sep;14(3):483-506 - PubMed
  13. Am J Public Health. 2004 Mar;94(3):361-6 - PubMed
  14. Int J Epidemiol. 2007 Jun;36(3):666-76 - PubMed
  15. Neuropsychologia. 2009 Aug;47(10):2015-28 - PubMed
  16. Annu Rev Psychol. 2012;63:201-26 - PubMed
  17. Psychol Aging. 2009 Sep;24(3):563-73 - PubMed
  18. Neurobiol Aging. 2009 Apr;30(4):507-14 - PubMed
  19. J Epidemiol Community Health. 2012 Jun;66(6):552-6 - PubMed
  20. Occup Environ Med. 2014 Oct;71(10):730-6 - PubMed
  21. Occup Environ Med. 2014 May;71(5):358-65 - PubMed
  22. J Int Neuropsychol Soc. 2010 Sep;16(5):754-60 - PubMed
  23. J Occup Health Psychol. 2014 Apr;19(2):231-42 - PubMed
  24. Perspect Psychol Sci. 2006 Mar;1(1):68-87 - PubMed
  25. Neuropsychology. 2010 Sep;24(5):563-72 - PubMed
  26. Exp Aging Res. 2003 Jan-Mar;29(1):33-45 - PubMed
  27. Res Nurs Health. 2009 Oct;32(5):540-50 - PubMed
  28. Psychol Sci. 2013 Feb 1;24(2):123-30 - PubMed
  29. Am J Epidemiol. 2009 Mar 1;169(5):596-605 - PubMed
  30. Am J Geriatr Psychiatry. 2012 Dec;20(12 ):1016-25 - PubMed
  31. Occup Environ Med. 2001 Aug;58(8):546-52 - PubMed

MeSH terms

Publication Types