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Jassem J. Bright and dark sides of evidence-based medicine. Pol Arch Med Wewn. 2016;126(5):347-52doi: 10.20452/pamw.3403.
Jassem, J. (2016). Bright and dark sides of evidence-based medicine. Polskie Archiwum Medycyny Wewnetrznej, 126(5), 347-52. https://doi.org/10.20452/pamw.3403
Jassem, Jacek. "Bright and dark sides of evidence-based medicine." Polskie Archiwum Medycyny Wewnetrznej vol. 126,5 (2016): 347-52. doi: https://doi.org/10.20452/pamw.3403
Jassem J. Bright and dark sides of evidence-based medicine. Pol Arch Med Wewn. 2016 May 31;126(5):347-52. doi: 10.20452/pamw.3403. Epub 2016 May 05. PMID: 27149007.
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Pol Arch Med Wewn. 2016 May 31;126(5):347-52. doi: 10.20452/pamw.3403. Epub 2016 May 05.

Bright and dark sides of evidence-based medicine.

Polskie Archiwum Medycyny Wewnetrznej

Jacek Jassem

PMID: 27149007 DOI: 10.20452/pamw.3403

Abstract

Evidence-based medicine is a current paradigm of practicing and teaching clinical medicine. This concept is widely believed to optimize clinical decision making by using the evidence derived from high-quality medical research, in particular from randomized clinical trials (RCTs) and their meta-analyses, as they are associated with a lower risk of bias compared with observational studies. However, RCTs are not devoid of limitations and their results may be distorted for various reasons. This article reviews the most common shortcomings of RCTs, with particular focus on publication bias.

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