Org Biomol Chem. 2016 Jun 15;14(24):5377-89. doi: 10.1039/c6ob00091f.
Organic & biomolecular chemistry
Adriana S Grossmann, Thomas Magauer
PMID: 27181133 DOI: 10.1039/c6ob00091f
This review highlights the chemistry of trihaloethene building blocks with a special focus on commercially available 1,1,2-trichloroethene. The topics surveyed herein include the use of trihaloethenes as C2-building blocks for transition metal-catalyzed coupling reactions, addition, elimination and cycloaddition reactions as well as natural product syntheses.