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Phys Chem Chem Phys. 2016 Jul 27;18(30):20104-8. doi: 10.1039/c6cp00608f.

Cysteine containing dipeptides show a metal specificity that matches the composition of seawater.

Physical chemistry chemical physics : PCCP

Luca Belmonte, Daniele Rossetto, Michele Forlin, Simone Scintilla, Claudia Bonfio, Sheref S Mansy

Affiliations

  1. CIBIO, University of Trento, via Sommarive 9, Povo, Italy. [email protected].

PMID: 27182665 DOI: 10.1039/c6cp00608f

Abstract

Model prebiotic dipeptide sequences were identified by bioinformatics and DFT and molecular dynamics calculations. The peptides were then synthesized and evaluated for metal affinity and specificity. Cysteine containing dipeptides were not associated with metal affinities that followed the Irving-Williams series but did follow the concentration trends found in seawater.

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