Display options
Cite
Smith LI, Dayal S, Murray J, et al. Attitudes towards breast conservation in patients aged over 70 with breast cancer. Springerplus. 2016;5:478doi: 10.1186/s40064-016-2133-5.
Smith, L. I., Dayal, S., Murray, J., & Lannigan, A. (2016). Attitudes towards breast conservation in patients aged over 70 with breast cancer. SpringerPlus, 5478. https://doi.org/10.1186/s40064-016-2133-5
Smith, L I, et al. "Attitudes towards breast conservation in patients aged over 70 with breast cancer." SpringerPlus vol. 5 (2016): 478. doi: https://doi.org/10.1186/s40064-016-2133-5
Smith LI, Dayal S, Murray J, Lannigan A. Attitudes towards breast conservation in patients aged over 70 with breast cancer. Springerplus. 2016 Apr 18;5:478. doi: 10.1186/s40064-016-2133-5. eCollection 2016. PMID: 27217993; PMCID: PMC4835403.
Copy Download .nbib Format: NLM
Share it on

Springerplus. 2016 Apr 18;5:478. doi: 10.1186/s40064-016-2133-5. eCollection 2016.

Attitudes towards breast conservation in patients aged over 70 with breast cancer.

SpringerPlus

L I Smith, S Dayal, J Murray, A Lannigan

Affiliations

  1. Department of Breast Surgery, Wishaw General Hospital, 50 Netherton Street, Wishaw, ML2 0DP UK.
  2. Department of General Surgery, Basingstoke and North Hampshire Hospital, Aldermaston Road, Basingstoke, Hampshire RG24 9NA UK.

PMID: 27217993 PMCID: PMC4835403 DOI: 10.1186/s40064-016-2133-5

Abstract

BACKGROUND: The majority of breast conserving surgery (BCS) is performed in younger women. There is little published information about the views of women aged over 70 regarding BCS. The aim of this study was to investigate the attitudes of this age group towards BCS, and factors which may influence their treatment decision-making.

METHODS: A questionnaire was sent to all patients who were aged 70 or over at the time they had breast cancer surgery in NHS Lanarkshire between 1999 and 2013. This detailed surgical options and recommendations, timing of decision making, treatment expectations, psychological and cosmetic concerns and other factors which may have influenced any decision made e.g. travel for radiotherapy and potential side effects.

RESULTS: Responses were received from 339 patients, 192 of whom had a mastectomy with the remaining undergoing BCS. In the mastectomy group 18 % (35) would have preferred to have BCS had it been an option, with 40 % (76) of group being happy to take neoadjuvant endocrine therapy to try and facilitate this. However, only 14 % (26) of patients would have considered neoadjuvant chemotherapy with the same aim. Almost half (82) of the mastectomy patients said that the risk of local recurrence following BCS was a factor which influenced their decision.

CONCLUSION: BCS is something that patients aged over 70 are interested in considering in the same way as younger patients. More than a third of patients requiring mastectomy would be willing to take neoadjuvant endocrine therapy to attempt to downstage their tumour to facilitate BCS.

Keywords: Breast cancer; Breast conserving surgery; Elderly

References

  1. N Engl J Med. 1995 Nov 30;333(22):1444-55 - PubMed
  2. J Clin Oncol. 2004 Oct 1;22(19):4002-9 - PubMed
  3. JAMA. 2001 Feb 21;285(7):885-92 - PubMed
  4. Lancet Oncol. 2012 Apr;13(4):e148-60 - PubMed
  5. J Clin Oncol. 2002 Feb 15;20(4):1008-16 - PubMed
  6. Br J Surg. 1991 Feb;78(2):213-7 - PubMed
  7. Br J Surg. 1991 May;78(5):591-4 - PubMed
  8. Ann Oncol. 2001 Nov;12(11):1527-32 - PubMed
  9. Ann Oncol. 1999 Jan;10(1):47-52 - PubMed
  10. Breast Cancer Res Treat. 1997 Jun;44(2):123-33 - PubMed
  11. Eur J Cancer. 1991;27(12):1539-42 - PubMed
  12. Anticancer Res. 1994 Sep-Oct;14(5B):2197-200 - PubMed
  13. J Clin Oncol. 1998 Aug;16(8):2672-85 - PubMed
  14. Ann Oncol. 1994 Sep;5(7):591-5 - PubMed
  15. Eur J Surg Oncol. 1994 Jun;20(3):207-14 - PubMed
  16. Br J Surg. 1996 Jun;83(6):816-9 - PubMed
  17. J Clin Epidemiol. 1992 May;45(5):473-85 - PubMed
  18. Arch Intern Med. 1996 Jan 8;156(1):85-90 - PubMed
  19. Breast Cancer Res Treat. 1997 Mar;43(1):27-31 - PubMed
  20. J Am Geriatr Soc. 2012 Mar;60(3):538-44 - PubMed
  21. J Natl Cancer Inst. 1993 Feb 3;85(3):190-9 - PubMed
  22. Br J Surg. 2003 Apr;90(4):388-99 - PubMed
  23. BMJ. 1992 Apr 18;304(6833):996-7 - PubMed
  24. Eur J Cancer. 1998 Feb;34(3):307-14 - PubMed
  25. Eur J Cancer. 1992;28A(4-5):908-10 - PubMed
  26. Breast. 2014 Jun;23(3):273-8 - PubMed
  27. J Am Coll Surg. 1998 Mar;186(3):269-74 - PubMed
  28. Cancer Treat Rev. 2014 Sep;40(8):1005-18 - PubMed
  29. Eur J Cancer. 2003 Feb;39(3):300-8 - PubMed
  30. World J Surg Oncol. 2014 Jul 22;12:230 - PubMed
  31. Br J Cancer. 2012 Sep 25;107(7):1195-202 - PubMed
  32. Cancer J Sci Am. 1997 Jan-Feb;3(1):6-12 - PubMed
  33. J Surg Oncol. 1995 Oct;60(2):80-2 - PubMed
  34. Eur J Cancer. 2003 May;39(7):945-51 - PubMed
  35. Ann Oncol. 1991 May;2(5):347-54 - PubMed
  36. Br J Cancer. 2004 Apr 19;90(8):1486-91 - PubMed
  37. Br J Surg. 1996 Jul;83(7):994-6 - PubMed

Publication Types