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World J Gastrointest Surg. 2016 Jun 27;8(6):427-35. doi: 10.4240/wjgs.v8.i6.427.

Impact of previous cyst-enterostomy on patients' outcome following resection of bile duct cysts.

World journal of gastrointestinal surgery

Mehdi Ouaissi, Reza Kianmanesh, Emilia Ragot, Jacques Belghiti, Pietro Majno, Gennaro Nuzzo, Remi Dubois, Yann Revillon, Daniel Cherqui, Daniel Azoulay, Christian Letoublon, François-René Pruvot, François Paye, Patrick Rat, Karim Boudjema, Adeline Roux, Jean-Yves Mabrut, Jean-François Gigot

Affiliations

  1. Mehdi Ouaissi, Department of General and Digestive Surgery, La Timone Hospital, 13009 Marseille, France.

PMID: 27358675 PMCID: PMC4919710 DOI: 10.4240/wjgs.v8.i6.427

Abstract

AIM: To analyze the impact of previous cyst-enterostomy of patients underwent congenital bile duct cysts (BDC) resection.

METHODS: A multicenter European retrospective study between 1974 and 2011 were conducted by the French Surgical Association. Only Todani subtypes I and IVb were included. Diagnostic imaging studies and operative and pathology reports underwent central revision. Patients with and without a previous history of cyst-enterostomy (CE) were compared.

RESULTS: Among 243 patients with Todani types I and IVb BDC, 16 had undergone previous CE (6.5%). Patients with a prior history of CE experienced a greater incidence of preoperative cholangitis (75% vs 22.9%, P < 0.0001), had more complicated presentations (75% vs 40.5%, P = 0.007), and were more likely to have synchronous biliary cancer (31.3% vs 6.2%, P = 0.004) than patients without a prior CE. Overall morbidity (75% vs 33.5%; P < 0.0008), severe complications (43.8% vs 11.9%; P = 0.0026) and reoperation rates (37.5% vs 8.8%; P = 0.0032) were also significantly greater in patients with previous CE, and their Mayo Risk Score, during a median follow-up of 37.5 mo (range: 4-372 mo) indicated significantly more patients with fair and poor results (46.1% vs 15.6%; P = 0.0136).

CONCLUSION: This is the large series to show that previous CE is associated with poorer short- and long-term results after Todani types I and IVb BDC resection.

Keywords: Bile duct cyst; Biliary disease; Congenital; Cyst-enterostomy; Long-term outcome

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