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J Cardiovasc Ultrasound. 2016 Jun;24(2):123-7. doi: 10.4250/jcu.2016.24.2.123. Epub 2016 Jun 22.

Assessment of Left Ventricular Volume and Function Using Real-Time 3D Echocardiography versus Angiocardiography in Children with Tetralogy of Fallot.

Journal of cardiovascular ultrasound

Faten M Abdel Aziz, Soha M Abdel Dayem, Reem I Ismail, Hebah Hassan, Aya M Fattouh

Affiliations

  1. Department of Pediatrics, Cairo University, Cairo, Egypt.
  2. Department of Pediatrics, National Research Centre, Cairo, Egypt.

PMID: 27358704 PMCID: PMC4925389 DOI: 10.4250/jcu.2016.24.2.123

Abstract

BACKGROUND: Evaluation of left ventricular (LV) size and function is one of the important reasons for performing echocardiography. Real time three dimensional echocardiography (RT3DE) is now available for a precise non-invasive ventricular volumetry. Aim of work was to validate RT3DE as a non-invasive cardiac imaging method for measurement of LV volumes using cardiac angiography as the reference technique.

METHODS: Prospective study on 40 consecutive patients with tetralogy of Fallot (TOF) referred for cardiac catheterization for preoperative assessment. Biplane cineangiography, conventional 2 dimensional echocardiography (2DE) and RT3DE were performed for the patients. A control group of 18 age and sex matched children was included and 2DE and RT3DE were performed for them.

RESULTS: The mean LV end diastolic volume (LVEDV) and LVEDV index (LVEDVI) measured by RT3DE of patients were lower than controls (p value = 0.004, 0.01, respectively). There was strong correlation between the mean value of the LVEDV and the LVEDVI measured by RT3DE and angiography (r = 0.97, p < 0.001). The mean value of LV ejection fraction measured by RT3DE was lower than that assessed by 2DE (50 ± 6.2%, 65 ± 4.6%, respectively, p value < 0.001) in the studied TOF cases. There was good intra- and inter-observer reliability for all measurements.

CONCLUSION: RT3DE is a noninvasive and feasible tool for measurement of LV volumes that strongly correlates with LV volumetry done by angiography in very young infants and children, and further studies needed.

Keywords: Echocardiography; Tetralogy of Fallot; Three-dimensional

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