Display options
Cite
Kim KC, Vo HP. Localized malignant pleural sarcomatoid mesothelioma misdiagnosed as benign localized fibrous tumor. J Thorac Dis. 2016;8(6):E379-84doi: 10.21037/jtd.2016.03.92.
Kim, K. C., & Vo, H. P. (2016). Localized malignant pleural sarcomatoid mesothelioma misdiagnosed as benign localized fibrous tumor. Journal of thoracic disease, 8(6), E379-84. https://doi.org/10.21037/jtd.2016.03.92
Kim, Kwan-Chang, and Vo, Hong-Phuc. "Localized malignant pleural sarcomatoid mesothelioma misdiagnosed as benign localized fibrous tumor." Journal of thoracic disease vol. 8,6 (2016): E379-84. doi: https://doi.org/10.21037/jtd.2016.03.92
Kim KC, Vo HP. Localized malignant pleural sarcomatoid mesothelioma misdiagnosed as benign localized fibrous tumor. J Thorac Dis. 2016 Jun;8(6):E379-84. doi: 10.21037/jtd.2016.03.92. PMID: 27293862; PMCID: PMC4885954.
Copy Download .nbib Format: NLM
Share it on

J Thorac Dis. 2016 Jun;8(6):E379-84. doi: 10.21037/jtd.2016.03.92.

Localized malignant pleural sarcomatoid mesothelioma misdiagnosed as benign localized fibrous tumor.

Journal of thoracic disease

Kwan-Chang Kim, Hong-Phuc Vo

Affiliations

  1. 1 Department of Thoracic and Caridiovascular Surgery, School of Medicine, Ewha Womans University, Seoul, Korea ; 2 Department of Surgery, Windsor University, School of Medicine, St. Kitts Nevis, USA.

PMID: 27293862 PMCID: PMC4885954 DOI: 10.21037/jtd.2016.03.92

Abstract

Localized malignant pleural mesothelioma (LMPM) is a rare tumor with good prognosis by surgical resection. We report an atypical case of malignant pleural sarcomatoid mesothelioma (SM) in an asymptomatic 65-year-old woman, who had no history of exposure to asbestos. She presented with a small pleural mass without pleural effusion and was misdiagnosed as a benign localized fibrous tumor (BLFT) on pathologic examination through a surgical tumor specimen. However, seven months later, the patient returned with serious cancerous symptoms. A large recurrent tumor mass was found within the chest wall invading at the old surgical resection site. SM, a subtype of LMPM, was confirmed with histopathogy and immunohistochemisty. In conclusion, malignant pleural mesothelioma (MPM) can present with typical radiologic finding similar to a BLFT, and has a wide histopathologic presentation in biopsy specimen. A thorough pathologic investigation should be attempted even when a pleural mass resembles benign, localized, and small on radiologic studies.

Keywords: Pleura; computed tomography (CT); lobectomy; mesothelioma; pathology

References

  1. Radiographics. 2004 Jan-Feb;24(1):105-19 - PubMed
  2. Br J Cancer. 2004 Mar 8;90(5):1022-4 - PubMed
  3. AJR Am J Roentgenol. 1990 Nov;155(5):965-9 - PubMed
  4. Lancet Oncol. 2013 Oct;14(11):1104-11 - PubMed
  5. Chest Surg Clin N Am. 1994 Feb;4(1):113-26 - PubMed
  6. Case Rep Oncol. 2014 Jun 14;7(2):389-92 - PubMed
  7. Chirurg. 2013 Jun;84(6):487-91 - PubMed
  8. Eur J Cardiothorac Surg. 1998 Nov;14(5):453-9 - PubMed
  9. Am J Surg Pathol. 1994 Apr;18(4):357-63 - PubMed
  10. Arch Pathol Lab Med. 2013 May;137(5):647-67 - PubMed
  11. Ann Cardiothorac Surg. 2012 Nov;1(4):457-61 - PubMed
  12. J Thorac Oncol. 2009 Aug;4(8):1038-40 - PubMed
  13. Am J Respir Crit Care Med. 2005 Oct 15;172(8):1019-25 - PubMed
  14. Surgery. 2013 Jun;153(6):779-86 - PubMed
  15. Eur J Radiol. 2012 Dec;81(12 ):4203-10 - PubMed
  16. Br J Cancer. 2012 Mar 13;106(6):1027-32 - PubMed
  17. Ann Thorac Cardiovasc Surg. 2007 Aug;13(4):262-6 - PubMed
  18. Semin Thorac Cardiovasc Surg. 2009 Summer;21(2):132-48 - PubMed
  19. Mod Pathol. 2005 Jan;18(1):105-10 - PubMed
  20. Semin Oncol. 2002 Feb;29(1):2-17 - PubMed
  21. Pathol Int. 2008 Feb;58(2):75-83 - PubMed
  22. Medicine (Baltimore). 2015 Sep;94(38):e1548 - PubMed
  23. Ann Thorac Surg. 2008 Jan;85(1):257-64; discussion 264 - PubMed
  24. AJR Am J Roentgenol. 1993 Sep;161(3):533-7 - PubMed
  25. Mod Pathol. 2010 Mar;23(3):470-9 - PubMed
  26. Gen Thorac Cardiovasc Surg. 2012 Jul;60(7):468-74 - PubMed
  27. Am J Epidemiol. 2004 Jan 15;159(2):107-12 - PubMed
  28. Ann Thorac Cardiovasc Surg. 2007 Oct;13(5):349-51 - PubMed
  29. N Engl J Med. 2005 Oct 13;353(15):1591-603 - PubMed
  30. J Thorac Cardiovasc Surg. 2009 Jul;138(1):19-25 - PubMed
  31. J Thorac Oncol. 2009 Jun;4(6):746-50 - PubMed
  32. Ann Oncol. 2010 May;21 Suppl 5:v126-8 - PubMed
  33. Expert Rev Respir Med. 2010 Jun;4(3):363-72 - PubMed
  34. Tumori. 2016 Mar-Apr;102(2):127-30 - PubMed
  35. Thorac Cardiovasc Surg. 2012 Oct;60(7):468-73 - PubMed
  36. Histopathology. 2009 May;54(6):667-76 - PubMed

Publication Types