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Ntanasis-Stathopoulos I, Triantafyllou S, Xiromeritou V, et al. Esophageal remnant cancer 35 years after acidic caustic injury: A case report. Int J Surg Case Rep. 2016;25:215-7doi: 10.1016/j.ijscr.2016.06.051.
Ntanasis-Stathopoulos, I., Triantafyllou, S., Xiromeritou, V., Bliouras, N., Loizou, C., & Theodorou, D. (2016). Esophageal remnant cancer 35 years after acidic caustic injury: A case report. International journal of surgery case reports, 25215-7. https://doi.org/10.1016/j.ijscr.2016.06.051
Ntanasis-Stathopoulos, Ioannis, et al. "Esophageal remnant cancer 35 years after acidic caustic injury: A case report." International journal of surgery case reports vol. 25 (2016): 215-7. doi: https://doi.org/10.1016/j.ijscr.2016.06.051
Ntanasis-Stathopoulos I, Triantafyllou S, Xiromeritou V, Bliouras N, Loizou C, Theodorou D. Esophageal remnant cancer 35 years after acidic caustic injury: A case report. Int J Surg Case Rep. 2016;25:215-7. doi: 10.1016/j.ijscr.2016.06.051. Epub 2016 Jul 01. PMID: 27394396; PMCID: PMC4941112.
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Int J Surg Case Rep. 2016;25:215-7. doi: 10.1016/j.ijscr.2016.06.051. Epub 2016 Jul 01.

Esophageal remnant cancer 35 years after acidic caustic injury: A case report.

International journal of surgery case reports

Ioannis Ntanasis-Stathopoulos, Stamatina Triantafyllou, Vasiliki Xiromeritou, Nikolaos Bliouras, Chriso Loizou, Dimitrios Theodorou

Affiliations

  1. Department of Foregut Surgery, 1st Propaedeutic Surgical Clinic, "Hippokration" General Hospital of Athens, National and Kapodistrian University of Athens, 114 Vas. Sofias Av., 11527 Athens, Greece. Electronic address: [email protected].
  2. Department of Foregut Surgery, 1st Propaedeutic Surgical Clinic, "Hippokration" General Hospital of Athens, National and Kapodistrian University of Athens, 114 Vas. Sofias Av., 11527 Athens, Greece.
  3. Department of Gastroenterology, "Hippokration" General Hospital of Athens, Athens, Greece.

PMID: 27394396 PMCID: PMC4941112 DOI: 10.1016/j.ijscr.2016.06.051

Abstract

INTRODUCTION: Esophageal squamous cell carcinoma has been described as a long-term consequence following ingestion of corrosive substances.

PRESENTATION OF CASE: We report a rare case of a 62-year-old female patient with a history of acidic caustic injury 35 years ago, for which she had undergone near total esophagogastrectomy with right colon interposition. Recently, she presented with worsening dysphagia, weight loss, neck swelling and chest pain. After the diagnostic workup, an invasive squamous cell carcinoma of the esophagus was confirmed. To our knowledge, this is the first such report in the literature.

DISCUSSION: The risk for esophageal carcinoma increases substantially after ingestion of caustic substances. It is notable that distinct patterns of carcinogenesis between acids and alkalis may be postulated, since the corresponding pathophysiological impact of each one differ significantly. Although such esophageal cancers tend to have good prognosis due to early detection, both the diagnostic and therapeutic strategy may be challenging due to the limited available data in this field. Surgical treatment does not seem to eliminate the risk of cancer, as evident upon the present case report.

CONCLUSION: Optimal management of esophageal corrosive injuries remains a debatable issue in terms of choosing between conservative therapy and surgical intervention. For this reason, the need for long-term follow up regardless the ingested substance and the preferred therapeutic approach is highlighted.

Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Keywords: Case report; Chemical burns; Esophageal carcinoma; Squamous cell carcinoma

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