Display options
Cite
Lotter C, Heiland JJ, Stein V, et al. Evaluation of Pressure Stable Chip-to-Tube Fittings Enabling High-Speed Chip-HPLC with Mass Spectrometric Detection. Anal Chem. 2016;88(15):7481-6doi: 10.1021/acs.analchem.6b01907.
Lotter, C., Heiland, J. J., Stein, V., Klimkait, M., Queisser, M., & Belder, D. (2016). Evaluation of Pressure Stable Chip-to-Tube Fittings Enabling High-Speed Chip-HPLC with Mass Spectrometric Detection. Analytical chemistry, 88(15), 7481-6. https://doi.org/10.1021/acs.analchem.6b01907
Lotter, Carsten, et al. "Evaluation of Pressure Stable Chip-to-Tube Fittings Enabling High-Speed Chip-HPLC with Mass Spectrometric Detection." Analytical chemistry vol. 88,15 (2016): 7481-6. doi: https://doi.org/10.1021/acs.analchem.6b01907
Lotter C, Heiland JJ, Stein V, Klimkait M, Queisser M, Belder D. Evaluation of Pressure Stable Chip-to-Tube Fittings Enabling High-Speed Chip-HPLC with Mass Spectrometric Detection. Anal Chem. 2016 Aug 02;88(15):7481-6. doi: 10.1021/acs.analchem.6b01907. Epub 2016 Jul 20. PMID: 27397738.
Copy Download .nbib Format: NLM
Share it on

Anal Chem. 2016 Aug 02;88(15):7481-6. doi: 10.1021/acs.analchem.6b01907. Epub 2016 Jul 20.

Evaluation of Pressure Stable Chip-to-Tube Fittings Enabling High-Speed Chip-HPLC with Mass Spectrometric Detection.

Analytical chemistry

Carsten Lotter, Josef J Heiland, Volkmar Stein, Michael Klimkait, Marco Queisser, Detlev Belder

Affiliations

  1. Institute of Analytical Chemistry, University of Leipzig , Linnéstraße 3, 04103 Leipzig, Germany.
  2. Fraunhofer ICT-IMM , Carl-Zeiss-Str. 18-20, 55129 Mainz, Germany.
  3. Fraunhofer IZM , Gustav-Meyer-Allee 25, 13355 Berlin, Germany.

PMID: 27397738 DOI: 10.1021/acs.analchem.6b01907

Abstract

Appropriate chip-to-tube interfacing is an enabling technology for high-pressure and high-speed liquid chromatography on chip. For this purpose, various approaches, to connect pressure resistant glass chips with HPLC pumps working at pressures of up to 500 bar, were examined. Three side-port and one top-port connection approach were evaluated with regard to pressure stability and extra column band broadening. A clamp-based top-port approach enabled chip-HPLC-MS analysis of herbicides at the highest pressure and speed.

Publication Types