Display options
Cite
Elkourashy SA, Nashwan AJ, Alam SI, et al. Aggressive Lymphoma "Sarcoma Mimicker" Originating in the Gluteus and Adductor Muscles: A Case Report and Literature Review. Clin Med Insights Case Rep. 2016;9:47-53doi: 10.4137/CCRep.S39052.
Elkourashy, S. A., Nashwan, A. J., Alam, S. I., Ammar, A. A., El Sayed, A. M., Omri, H. E., & Yassin, M. A. (2016). Aggressive Lymphoma "Sarcoma Mimicker" Originating in the Gluteus and Adductor Muscles: A Case Report and Literature Review. Clinical medicine insights. Case reports, 947-53. https://doi.org/10.4137/CCRep.S39052
Elkourashy, Sarah A, et al. "Aggressive Lymphoma "Sarcoma Mimicker" Originating in the Gluteus and Adductor Muscles: A Case Report and Literature Review." Clinical medicine insights. Case reports vol. 9 (2016): 47-53. doi: https://doi.org/10.4137/CCRep.S39052
Elkourashy SA, Nashwan AJ, Alam SI, Ammar AA, El Sayed AM, Omri HE, Yassin MA. Aggressive Lymphoma "Sarcoma Mimicker" Originating in the Gluteus and Adductor Muscles: A Case Report and Literature Review. Clin Med Insights Case Rep. 2016 Jul 05;9:47-53. doi: 10.4137/CCRep.S39052. eCollection 2016. PMID: 27398038; PMCID: PMC4934407.
Copy Download .nbib Format: NLM
Share it on

Clin Med Insights Case Rep. 2016 Jul 05;9:47-53. doi: 10.4137/CCRep.S39052. eCollection 2016.

Aggressive Lymphoma "Sarcoma Mimicker" Originating in the Gluteus and Adductor Muscles: A Case Report and Literature Review.

Clinical medicine insights. Case reports

Sarah A Elkourashy, Abdulqadir J Nashwan, Syed I Alam, Adham A Ammar, Ahmed M El Sayed, Halima El Omri, Mohamed A Yassin

Affiliations

  1. Clinical Fellow, Department of Hematology and BMT, National Center for Cancer Care and Research (NCCCR) - Hamad Medical Corporation (HMC), Doha, Qatar.
  2. Nurse Educator, Nursing Department, National Center for Cancer Care and Research (NCCCR) - Hamad Medical Corporation (HMC), Doha, Qatar.
  3. Radiology Specialist, Hamad Medical Corporation (HMC), Doha, Qatar.
  4. Laboratory Consultant, Hamad Medical Corporation (HMC), Doha, Qatar.
  5. Orthopedic Consultant, Department of Surgery, Hamad Medical Corporation (HMC), Doha, Qatar.
  6. Hematology Consultant, Department of Hematology and BMT, National Center for Cancer Care and Research (NCCCR)-Hamad Medical Corporation (HMC), Doha, Qatar.

PMID: 27398038 PMCID: PMC4934407 DOI: 10.4137/CCRep.S39052

Abstract

Extranodal lymphoma (ENL) occurs in approximately 30%-40% of all patients with non-Hodgkin lymphoma and has been described in almost all organs and tissues. However, diffuse large B-cell lymphoma is the most common histological subtype of non-Hodgkin lymphoma, primarily arising in the retroperitoneal region. In this article, we report a rare case of an adult male diagnosed with primary diffuse large B-cell lymphoma of the gluteal and adductor muscles with aggressive bone involvement. All appropriate radiological and histopathological studies were done for diagnosis and staging. After discussion with the lymphoma multidisciplinary team, it was agreed to start on R-CHOP protocol (rituximab, cyclophosphamide, doxorubicin (Adriamycin), vincristine (Oncovin®), and prednisone) as the standard of care, which was later changed to R-CODOX-M/R-IVAC protocol (rituximab, cyclophosphamide, vincristine (Oncovin®), doxorubicin, and high-dose methotrexate alternating with rituximab, ifosfamide, etoposide, and high-dose cytarabine) due to inadequate response. Due to the refractory aggressive nature of the disease, subsequent decision of the multidisciplinary team was salvage chemotherapy and autologous stem cell transplant. The aim of this case report was to describe and evaluate the clinical presentation and important radiological features of extranodal lymphoma affecting the musculoskeletal system.

Keywords: extranodal; gluteal muscle; lymphoma; non-Hodgkin lymphoma

References

  1. AJR Am J Roentgenol. 2004 Jun;182(6):1579-86 - PubMed
  2. Chir Organi Mov. 2004 Oct-Dec;89(4):329-38 - PubMed
  3. South Med J. 2006 Oct;99(10):1149-50 - PubMed
  4. Medicine (Baltimore). 2015 May;94(18):e833 - PubMed
  5. J Clin Oncol. 2014 Sep 20;32(27):3059-68 - PubMed
  6. Hum Pathol. 1996 Mar;27(3):253-7 - PubMed
  7. Chin Clin Oncol. 2015 Mar;4(1):10 - PubMed
  8. Int J Hematol Oncol Stem Cell Res. 2014 Jul 1;8(3):55-7 - PubMed
  9. Oncol Lett. 2015 Oct;10(4):2156-2160 - PubMed
  10. Oncol Lett. 2012 Nov;4(5):1023-1026 - PubMed
  11. ANZ J Surg. 2003 Jan-Feb;73(1-2):26-30 - PubMed
  12. Oncol Lett. 2015 Sep;10(3):1686-1688 - PubMed
  13. J Plast Reconstr Aesthet Surg. 2007;60(6):646-54 - PubMed
  14. Am J Surg Pathol. 1987 May;11(5):359-66 - PubMed
  15. Ann Oncol. 2003 Jan;14(1):131-9 - PubMed
  16. Rinsho Ketsueki. 1999 Feb;40(2):140-4 - PubMed
  17. AJNR Am J Neuroradiol. 1998 Nov-Dec;19(10 ):1849-51 - PubMed
  18. Recenti Prog Med. 1997 Apr;88(4):166-8 - PubMed
  19. Eur J Cancer. 1994;30A(12):1760-4 - PubMed
  20. Radiographics. 2010 Jan;30(1):269-91 - PubMed
  21. Skeletal Radiol. 1997 Oct;26(10 ):622-5 - PubMed
  22. Henry Ford Hosp Med J. 1988;36(1):61-3 - PubMed
  23. Int J Surg Case Rep. 2015;7C:161-4 - PubMed
  24. Aust Vet J. 2005 Oct;83(10):612-5 - PubMed

Publication Types