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Clin Case Rep. 2016 Apr 21;4(6):545-8. doi: 10.1002/ccr3.539. eCollection 2016 Jun.

Capecitabine-related liver lesions: sinusoidal dilatation mimicking liver metastasis.

Clinical case reports

Katherine Groom, Marta Penna, Dhili Arul, Michael Steward, Pauline Leonard, Jonathan Wilson

Affiliations

  1. Department of General Surgery Whittington Health Magdala Avenue London N19 5NF UK.

PMID: 27398193 PMCID: PMC4891475 DOI: 10.1002/ccr3.539

Abstract

A 30-year-old lady treated with capecitabine for primary colon adenocarcinoma developed liver lesions suspicious for metastasis. Liver biopsies showed sinusoidal dilatation thought to be secondary to capecitabine. This case highlights the importance of differentiating between benign and malignant liver lesions during cancer surveillance preventing unnecessary liver resections for benign disease.

Keywords: Capecitabine; colonic adenocarcinoma; liver lesions; sinusoidal dilatation

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