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Cendes F, Theodore WH, Brinkmann BH, et al. Neuroimaging of epilepsy. Handb Clin Neurol. 2016;136:985-1014doi: 10.1016/B978-0-444-53486-6.00051-X.
Cendes, F., Theodore, W. H., Brinkmann, B. H., Sulc, V., & Cascino, G. D. (2016). Neuroimaging of epilepsy. Handbook of clinical neurology, 136985-1014. https://doi.org/10.1016/B978-0-444-53486-6.00051-X
Cendes, Fernando, et al. "Neuroimaging of epilepsy." Handbook of clinical neurology vol. 136 (2016): 985-1014. doi: https://doi.org/10.1016/B978-0-444-53486-6.00051-X
Cendes F, Theodore WH, Brinkmann BH, Sulc V, Cascino GD. Neuroimaging of epilepsy. Handb Clin Neurol. 2016;136:985-1014. doi: 10.1016/B978-0-444-53486-6.00051-X. PMID: 27430454; PMCID: PMC5256664.
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Handb Clin Neurol. 2016;136:985-1014. doi: 10.1016/B978-0-444-53486-6.00051-X.

Neuroimaging of epilepsy.

Handbook of clinical neurology

Fernando Cendes, William H Theodore, Benjamin H Brinkmann, Vlastimil Sulc, Gregory D Cascino

Affiliations

  1. University of Campinas, Department of Neurology, Campinas, SP, Brazil.
  2. National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
  3. Division of Epilepsy, Department of Neurology, Mayo Clinic, Rochester, MN, USA.
  4. Department of Neurology, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Czech Republic.

PMID: 27430454 PMCID: PMC5256664 DOI: 10.1016/B978-0-444-53486-6.00051-X

Abstract

Imaging is pivotal in the evaluation and management of patients with seizure disorders. Elegant structural neuroimaging with magnetic resonance imaging (MRI) may assist in determining the etiology of focal epilepsy and demonstrating the anatomical changes associated with seizure activity. The high diagnostic yield of MRI to identify the common pathological findings in individuals with focal seizures including mesial temporal sclerosis, vascular anomalies, low-grade glial neoplasms and malformations of cortical development has been demonstrated. Positron emission tomography (PET) is the most commonly performed interictal functional neuroimaging technique that may reveal a focal hypometabolic region concordant with seizure onset. Single photon emission computed tomography (SPECT) studies may assist performance of ictal neuroimaging in patients with pharmacoresistant focal epilepsy being considered for neurosurgical treatment. This chapter highlights neuroimaging developments and innovations, and provides a comprehensive overview of the imaging strategies used to improve the care and management of people with epilepsy.

© 2016 Elsevier B.V. All rights reserved.

Keywords: 18F-fluorodeoxyglucose–positron emission tomography (18F-FDG-PET); Epilepsy; computed tomography (CT); drug-resistant focal epilepsy; ictal single photon emission computed tomography (SPECT); magnetic resonance imaging (MRI); surgical treatment of epilepsy

References

  1. Neurology. 2010 Feb 16;74(7):553-7 - PubMed
  2. Neuroimage Clin. 2013 Sep 03;3:242-8 - PubMed
  3. Epilepsia. 2010 Aug;51(8):1365-73 - PubMed
  4. Seizure. 2008 Sep;17(6):514-23 - PubMed
  5. Epilepsy Res. 2014 Oct;108(8):1306-14 - PubMed
  6. Neurology. 2002 Jun 11;58(11):1646-51 - PubMed
  7. Ann Neurol. 1982 Dec;12(6):510-7 - PubMed
  8. Neuroimage. 2012 Feb 15;59(4):3582-93 - PubMed
  9. Epilepsy Res. 2014 Aug;108(6):1095-105 - PubMed
  10. Arch Neurol. 1994 Sep;51(9):932-6 - PubMed
  11. Neurology. 1997 Sep;49(3):774-8 - PubMed
  12. Seizure. 2006 Jan;15(1):56-63 - PubMed
  13. Epilepsia. 1999 Jan;40(1):26-9 - PubMed
  14. Ann Neurol. 1987 Jan;21(1):14-21 - PubMed
  15. Epilepsia. 2001 Jan;42(1):3-12 - PubMed
  16. Ann Neurol. 1992 Feb;31(2):138-46 - PubMed
  17. Neurology. 1999 Jan 1;52(1):137-46 - PubMed
  18. PLoS One. 2014 Jan 27;9(1):e85843 - PubMed
  19. Ann Neurol. 1990 Apr;27(4):406-13 - PubMed
  20. Arch Neurol. 1994 Feb;51(2):155-63 - PubMed
  21. Brain Pathol. 2015 May;25(3):248-55 - PubMed
  22. Brain. 2007 Feb;130(Pt 2):548-60 - PubMed
  23. J Nucl Med. 2003 Jul;44(7):1006-12 - PubMed
  24. Epilepsia. 2013 Feb;54(2):351-8 - PubMed
  25. Ann Neurol. 1983 Oct;14 (4):429-37 - PubMed
  26. Neurology. 2010 Jan 5;74(1):70-6 - PubMed
  27. Neurology. 1993 Oct;43(10 ):1998-2006 - PubMed
  28. Epilepsia. 2013 Dec;54(12 ):2143-50 - PubMed
  29. Epilepsia. 2000 Jul;41(7):843-9 - PubMed
  30. Neurology. 2000 Jan 11;54(1):171-9 - PubMed
  31. Epilepsia. 1993 Jul-Aug;34(4):764-71 - PubMed
  32. Epilepsia. 2007 Mar;48(3):579-88 - PubMed
  33. Neurology. 1998 Aug;51(2):465-71 - PubMed
  34. Epilepsia. 2011 Sep;52(9):1692-8 - PubMed
  35. Brain. 2009 Oct;132(Pt 10):2785-97 - PubMed
  36. Neurosurg Focus. 2013 Apr;34(4):E10 - PubMed
  37. Epilepsia. 2011 Jan;52(1):158-74 - PubMed
  38. AJNR Am J Neuroradiol. 1995 Feb;16(2):339-43 - PubMed
  39. Mol Imaging Biol. 2002 May;4(3):245-52 - PubMed
  40. Clin Neurophysiol. 2000 Oct;111(10):1802-8 - PubMed
  41. Epilepsy Behav. 2009 Jan;14 Suppl 1:32-7 - PubMed
  42. Epilepsy Res. 2008 Dec;82(2-3):190-3 - PubMed
  43. Ann Neurol. 1985 Feb;17(2):121-8 - PubMed
  44. Brain. 1998 Nov;121 ( Pt 11):2067-81 - PubMed
  45. PLoS One. 2013;8(1):e53204 - PubMed
  46. Brain. 2003 Jan;126(Pt 1):248-60 - PubMed
  47. Acta Neuropathol. 2014 Jul;128(1):39-54 - PubMed
  48. BMC Neurol. 2014 Oct 02;14:194 - PubMed
  49. Epilepsia. 2005 Oct;46(10 ):1654-60 - PubMed
  50. Nucl Med Commun. 1998 Jan;19(1):31-45 - PubMed
  51. Neurology. 2009 Aug 11;73(6):423-9 - PubMed
  52. Brain. 2005 Jun;128(Pt 6):1330-43 - PubMed
  53. J Neurol Neurosurg Psychiatry. 2002 Dec;73(6):643-7 - PubMed
  54. Ann Neurol. 1992 Dec;32(6):789-94 - PubMed
  55. Brain Dev. 2003 Dec;25(8):560-70 - PubMed
  56. Neurology. 2015 Oct 27;85(17):1467-74 - PubMed
  57. Epilepsy Res. 1992 Nov;13(2):129-39 - PubMed
  58. Epilepsia. 2012 Aug;53(8):1333-40 - PubMed
  59. Brain. 2009 Apr;132(Pt 4):999-1012 - PubMed
  60. PLoS One. 2013 Sep 13;8(9):e74052 - PubMed
  61. Epilepsia. 2011 Aug;52(8):1430-8 - PubMed
  62. Neurology. 2003 Mar 11;60(5):749-56 - PubMed
  63. Neurology. 2008 Nov 11;71(20):1594-601 - PubMed
  64. Neurology. 2013 Apr 16;80(16):1465-71 - PubMed
  65. Neurology. 1990 Nov;40(11):1670-7 - PubMed
  66. Epilepsia. 2000 Sep;41(9):1206-13 - PubMed
  67. Epileptic Disord. 2009 Sep;11(3):194-205 - PubMed
  68. Brain. 2012 Aug;135(Pt 8):2337-49 - PubMed
  69. Dev Med Child Neurol. 2002 Feb;44(2):107-11 - PubMed
  70. Neurology. 1999 Dec 10;53(9):2199-203 - PubMed
  71. Neurology. 1995 May;45(5):934-41 - PubMed
  72. Ann Neurol. 1999 Jul;46(1):88-94 - PubMed
  73. Epilepsia. 2006 Dec;47(12 ):2125-30 - PubMed
  74. Acta Neurol Scand. 2001 Jun;103(6):360-6 - PubMed
  75. Brain. 2012 May;135(Pt 5):1348-69 - PubMed
  76. Brain. 2004 Oct;127(Pt 10):2276-85 - PubMed
  77. Epilepsy Behav. 2014 Dec;41:91-7 - PubMed
  78. Epilepsia. 2011 Dec;52(12 ):2249-56 - PubMed
  79. Neurology. 2014 Jul 1;83(1):48-55 - PubMed
  80. Epilepsy Behav. 2013 Nov;29(2):386-9 - PubMed
  81. Eur J Nucl Med. 2000 Nov;27(11):1658-65 - PubMed
  82. Brain Pathol. 2012 May;22(3):350-79 - PubMed
  83. Arch Neurol. 2009 Dec;66(12):1491-9 - PubMed
  84. Epilepsia. 2013 May;54(5):793-800 - PubMed
  85. Acta Neuropathol. 2014 Jul;128(1):21-37 - PubMed
  86. Epilepsia. 2012 Feb;53(2):342-8 - PubMed
  87. Neurology. 2013 Aug 13;81(7):674-80 - PubMed
  88. J Nucl Med. 2012 Sep;53(9):1375-82 - PubMed
  89. Lancet Neurol. 2013 Aug;12 (8):777-85 - PubMed
  90. Lancet. 1988 Oct 15;2(8616):863-6 - PubMed
  91. Neurology. 2005 Oct 11;65(7):1026-31 - PubMed
  92. Epilepsy Res. 2010 May;89(2-3):310-8 - PubMed
  93. Ann Neurol. 1988 Mar;23(3):231-7 - PubMed
  94. J Nucl Med. 2012 Feb;53(2):234-40 - PubMed
  95. Arq Neuropsiquiatr. 2007 Jun;65(2A):196-201 - PubMed
  96. Arch Neurol. 2004 Jul;61(7):1074-8 - PubMed
  97. Epilepsia. 2007 Aug;48(8):1526-30 - PubMed
  98. Curr Opin Neurol. 2007 Apr;20(2):194-202 - PubMed
  99. Neurology. 1985 May;35(5):684-90 - PubMed
  100. Neurology. 2004 Apr 27;62(8):1343-51 - PubMed
  101. Epilepsia. 2004;45 Suppl 4:32-4 - PubMed
  102. Neurosurgery. 2008 Sep;63(3):498-505; discussion 505-6 - PubMed
  103. Epilepsia. 2009 Sep;50(9):2053-60 - PubMed
  104. Lancet. 1993 Jan 23;341(8839):238 - PubMed
  105. J Nucl Med. 2005 Jul;46(7):1128-35 - PubMed
  106. JAMA Neurol. 2013 Aug;70(8):1003-8 - PubMed
  107. Am J Nucl Med Mol Imaging. 2014 Aug 15;4(5):459-70 - PubMed
  108. Neurosurg Focus. 2013 Jun;34(6):E6 - PubMed
  109. Expert Opin Med Diagn. 2012 Jul;6(4):295-308 - PubMed
  110. Neurology. 2000 Dec 12;55(11):1668-77 - PubMed
  111. Epilepsia. 2014 Aug;55(8):e80-4 - PubMed
  112. Continuum (Minneap Minn). 2013 Jun;19(3 Epilepsy):623-42 - PubMed
  113. Epilepsia. 2014 Sep;55(9):1415-22 - PubMed
  114. J Nucl Med. 2002 Sep;43(9):1167-74 - PubMed
  115. Epilepsia. 1997 Jan;38(1):74-80 - PubMed
  116. J Nucl Med. 2001 Aug;42(8):1158-65 - PubMed
  117. Epilepsia. 2010 Apr;51(4):703-7 - PubMed
  118. Epilepsia. 1999 Jan;40(1):30-7 - PubMed
  119. Ann Neurol. 1994 Dec;36(6):925-7 - PubMed
  120. Epilepsia. 1995 Jul;36(7):722-7 - PubMed
  121. Epileptic Disord. 2012 Dec;14 (4):404-13 - PubMed
  122. Neurology. 2000 May 9;54(9):1811-21 - PubMed
  123. Epilepsia. 2001 Jan;42(1):130-2 - PubMed
  124. Epilepsia. 2004 Apr;45(4):367-76 - PubMed
  125. Epilepsia. 2010 Apr;51(4):676-85 - PubMed
  126. Arch Neurol. 1997 Feb;54(2):129-36 - PubMed
  127. Epilepsia. 2005 Sep;46(9):1450-64 - PubMed
  128. J Nucl Med. 2014 Jul;55(7):1099-105 - PubMed
  129. Ann Neurol. 1991 Jul;30(1):3-11 - PubMed
  130. Brain. 2004 Apr;127(Pt 4):900-13 - PubMed
  131. Epilepsia. 2008 May;49(5):758-64 - PubMed
  132. J Neurol Neurosurg Psychiatry. 1971 Aug;34(4):369-87 - PubMed
  133. Seizure. 2007 Sep;16(6):509-20 - PubMed
  134. Epilepsia. 2007 Feb;48(2):278-85 - PubMed
  135. Ann Neurol. 1987 Jan;21(1):4-13 - PubMed
  136. Epilepsia. 2012 Jan;53(1):129-33 - PubMed
  137. J Child Neurol. 2007 Feb;22(2):232-7 - PubMed
  138. Neurology. 2000 Jan 25;54(2):332-9 - PubMed
  139. N Engl J Med. 2001 Aug 2;345(5):311-8 - PubMed
  140. J Nucl Med. 2005 Mar;46(3):540-7 - PubMed
  141. Epilepsia. 2002 Jun;43(6):596-602 - PubMed
  142. Neurology. 2013 Apr 30;80(18):1669-76 - PubMed
  143. Epilepsia. 2006 Sep;47(9):1550-7 - PubMed
  144. Brain. 2006 Aug;129(Pt 8):2047-60 - PubMed
  145. Ann Neurol. 1993 Aug;34(2):235-8 - PubMed
  146. J Magn Reson Imaging. 2009 Aug;30(2):256-62 - PubMed
  147. AJNR Am J Neuroradiol. 1990 Nov-Dec;11(6):1087-96 - PubMed
  148. J Nucl Med. 1995 Apr;36(4):684-9 - PubMed
  149. J Neurosci. 2011 Oct 19;31(42):15053-64 - PubMed
  150. Ann Neurol. 1996 Sep;40(3):446-50 - PubMed
  151. Neuroimage. 2005 Jan 1;24(1):101-10 - PubMed
  152. Neurology. 2000 Jun 27;54(12 ):2252-60 - PubMed
  153. Epilepsy Res. 2011 Nov;97(1-2):183-9 - PubMed
  154. Neuroradiology. 2013 May;55(5):541-50 - PubMed
  155. Epilepsia. 2014 May;55(5):699-706 - PubMed
  156. J Neuroimaging. 2013 Jan;23 (1):129-31 - PubMed
  157. Neurology. 2014 Oct 7;83(15):1326-31 - PubMed
  158. Biol Psychiatry. 2007 Dec 1;62(11):1258-64 - PubMed
  159. Radiology. 1996 Oct;201(1):97-105 - PubMed
  160. J Neurol Neurosurg Psychiatry. 2008 Jun;79(6):636-40 - PubMed
  161. Neurology. 1995 Jul;45(7):1396-402 - PubMed
  162. Epilepsia. 2011 Sep;52(9):1750-6 - PubMed
  163. Brain. 2009 Aug;132(Pt 8):2102-13 - PubMed
  164. J Nucl Med. 2013 Aug;54(8):1270-7 - PubMed
  165. Epilepsia. 2011 Dec;52(12 ):2239-48 - PubMed
  166. Neurology. 1995 Oct;45(10 ):1841-7 - PubMed
  167. Neurology. 2012 Sep 18;79(12):1244-51 - PubMed
  168. Neurology. 2002 Mar 12;58(5):717-22 - PubMed
  169. Arch Neurol. 1992 Jun;49(6):617-23 - PubMed
  170. Epilepsia. 2014 Dec;55(12 ):1926-33 - PubMed
  171. Neurology. 1998 Feb;50(2):445-54 - PubMed
  172. Cerebrovasc Brain Metab Rev. 1989 Winter;1(4):288-318 - PubMed
  173. Epilepsia. 1997 Nov;38(11):1255-6 - PubMed
  174. Nat Rev Neurol. 2011 Feb;7(2):99-108 - PubMed

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