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Wright AC, Bohning DE, Spicer KM. Phosphorus metabolites in human skin and muscle obtained by phosphorus-31 magnetic resonance spectroscopy. Skin Res Technol. 1997;3(1):66-72doi: 10.1111/j.1600-0846.1997.tb00163.x.
Wright, A. C., Bohning, D. E., & Spicer, K. M. (1997). Phosphorus metabolites in human skin and muscle obtained by phosphorus-31 magnetic resonance spectroscopy. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 3(1), 66-72. https://doi.org/10.1111/j.1600-0846.1997.tb00163.x
Wright, A C, et al. "Phosphorus metabolites in human skin and muscle obtained by phosphorus-31 magnetic resonance spectroscopy." Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) vol. 3,1 (1997): 66-72. doi: https://doi.org/10.1111/j.1600-0846.1997.tb00163.x
Wright AC, Bohning DE, Spicer KM. Phosphorus metabolites in human skin and muscle obtained by phosphorus-31 magnetic resonance spectroscopy. Skin Res Technol. 1997 Feb;3(1):66-72. doi: 10.1111/j.1600-0846.1997.tb00163.x. PMID: 27333177.
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Skin Res Technol. 1997 Feb;3(1):66-72. doi: 10.1111/j.1600-0846.1997.tb00163.x.

Phosphorus metabolites in human skin and muscle obtained by phosphorus-31 magnetic resonance spectroscopy.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)

A C Wright, D E Bohning, K M Spicer

Affiliations

  1. Department of Radiology, Medical University of South Carolina, Charleston, South Carolina, USA.

PMID: 27333177 DOI: 10.1111/j.1600-0846.1997.tb00163.x

Abstract

BACKGROUND/AIMS: Characterization of skin phosphometabol-ism in vivo by non-invasive magnetic resonance spectroscopy (MRS) might allow assessment of ischemic or irradiative damage.

METHODS: Based on a study of 17 healthy volunteers, we present statistical analyses for intra- and inter-tissue metabolite concentration ratios, as well as for pH and [Mg(2+) ].

RESULTS: Results contrasted steady-state energy metabolism in skin and muscle, showing lower phosphocreatine/ATP, higher percentage of inorganic phosphate, phosphodiesters and phos-phomonoesters, and higher pH and [Mg(2+) ] in skin than in muscle.

CONCLUSION: Results were consistent with known skin physiology and structure and suggested an inverse relationship between skin phosphodiester levels and melanin.

Keywords: human skin; metabolism; phosphorus spectroscopy

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