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Tuberc Respir Dis (Seoul). 2016 Jul;79(3):184-7. doi: 10.4046/trd.2016.79.3.184. Epub 2016 Jul 01.

IgG4-Related Lung Disease without Elevation of Serum IgG4 Level: A Case Report.

Tuberculosis and respiratory diseases

Min Kyu Kang, Yongseon Cho, Minsoo Han, Sun Young Jung, Kyoung Min Moon, Jinyoung Kim, Ju Ri Kim, Dong-Kyu Lee, Jun Hyung Park, So Hee Chung

Affiliations

  1. Division of Pulmonary Medicine, Department of Internal Medicine, Eulji University Hospital, Daejeon, Korea.

PMID: 27433179 PMCID: PMC4943903 DOI: 10.4046/trd.2016.79.3.184

Abstract

Since IgG4-related pancreatitis was first reported in 2001, IgG4-related disease has been identified in other organs such as salivary gland, gallbladder, thyroid, retroperitoneum and kidney; but lung invasion is rare. A 63-year-old man presented with hemoptysis at the pulmonary clinic and chest computed tomography revealed about 4.1 cm irregular shaped mass with spiculated margin at the left upper lobe. Despite no elevation of serum IgG4 level, he was finally diagnosed as IgG4-related lung disease by transthoracic needle biopsy. After treatment with oral glucocorticoids, hemoptysis disappeared and the size of lung mass was decreased.

Keywords: Hemoptysis; Immunoglobulins; Lung Diseases

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