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Fasanya AA, Pedersen FT, Alhassan S, et al. Cytomegalovirus Cutaneous Infection in an Immunocompromised Patient. Cureus. 2016;8(5):e598doi: 10.7759/cureus.598.
Fasanya, A. A., Pedersen, F. T., Alhassan, S., Adjapong, O., & Thirumala, R. (2016). Cytomegalovirus Cutaneous Infection in an Immunocompromised Patient. Cureus, 8(5), e598. https://doi.org/10.7759/cureus.598
Fasanya, Adebayo A, et al. "Cytomegalovirus Cutaneous Infection in an Immunocompromised Patient." Cureus vol. 8,5 (2016): e598. doi: https://doi.org/10.7759/cureus.598
Fasanya AA, Pedersen FT, Alhassan S, Adjapong O, Thirumala R. Cytomegalovirus Cutaneous Infection in an Immunocompromised Patient. Cureus. 2016 May 03;8(5):e598. doi: 10.7759/cureus.598. PMID: 27335710; PMCID: PMC4895079.
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Cureus. 2016 May 03;8(5):e598. doi: 10.7759/cureus.598.

Cytomegalovirus Cutaneous Infection in an Immunocompromised Patient.

Cureus

Adebayo A Fasanya, Faye T Pedersen, Sulaiman Alhassan, Opoku Adjapong, Raghukumar Thirumala

Affiliations

  1. Pulmonary and Critical Care Medicine, Allegheny General Hospital.
  2. Department of Emergency Medicine, Allegheny General Hospital.
  3. Pathology, Allegheny General Hospital.

PMID: 27335710 PMCID: PMC4895079 DOI: 10.7759/cureus.598

Abstract

Cytomegalovirus (CMV), a member of the Herpesviridae family, is an opportunistic infection with a typically benign course in the healthy host but has a more ominous course in the immunocompromised population. CMV infection commonly affects the visceral organs, particularly the respiratory and the gastrointestinal tract. CMV cutaneous lesions are rare and can be easily missed. We present a case of a 76-year-old woman presenting with a diffuse non-pruritic macular lesion with scattered vesicles and bullae, which was initially treated as a varicella zoster virus infection and herpes simplex viral infection, but was later found on biopsy to be due to cytomegalovirus. She has a history of Sjögren's syndrome, interstitial lung disease, and being on chronic immunosuppression therapy. This case highlights the importance of considering CMV infection in the differential diagnosis of vesicular skin lesions in immunocompromised patients. Based on a PubMed search for "cutaneous cytomegalovirus", "cutaneous CMV", "cytomegalovirus skin", and "skin CMV" in material published in the last 20 years (from 1996 to 2016) and reviewing any applicable referenced material outside of those dates, cases of cutaneous CMV are not well documented.

Keywords: cmv; cutaneous; cytomegalovirus; immunocompromised; skin and soft tissue infection; valganciclovir; vesicles and bullae

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