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Int J Surg Case Rep. 2016;25:128-31. doi: 10.1016/j.ijscr.2016.05.046. Epub 2016 Jun 29.

Massive gastrointestinal bleeding in AIDS patients secondary to histoplasma and cytomegalovirus infection.

International journal of surgery case reports

Marco Antonio Bruno, Matías Parodi, Ignacio Olmedo, Héctor Picón Molina, Rafael Palencia, Alejandro Doniquian

Affiliations

  1. General Surgery Service, University Clinic Reina Fabiola, Catholic University of Córdoba, Oncativo 1248 street, Córdoba Capital, Argentina. Electronic address: [email protected].
  2. General Surgery Service, University Clinic Reina Fabiola, Catholic University of Córdoba, Oncativo 1248 street, Córdoba Capital, Argentina. Electronic address: [email protected].
  3. General Surgery Service, University Clinic Reina Fabiola, Catholic University of Córdoba, Oncativo 1248 street, Córdoba Capital, Argentina. Electronic address: [email protected].
  4. General Surgery Service, University Clinic Reina Fabiola, Catholic University of Córdoba, Oncativo 1248 street, Córdoba Capital, Argentina. Electronic address: [email protected].
  5. General Surgery Service, University Clinic Reina Fabiola, Catholic University of Córdoba, Oncativo 1248 street, Córdoba Capital, Argentina. Electronic address: [email protected].
  6. General Surgery Service, University Clinic Reina Fabiola, Catholic University of Córdoba, Oncativo 1248 street, Córdoba Capital, Argentina. Electronic address: [email protected].

PMID: 27372024 PMCID: PMC4930355 DOI: 10.1016/j.ijscr.2016.05.046

Abstract

INTRODUCTION: The Cytomegalovirus (CMV) is a virus that affects the host and remains latent. When cellular immunity is suppressed, the virus is reactivated and can cause an asymptomatic or devastating infection in immunosuppressed patients. On the other hand, Histoplasmosis is typically a respiratory condition. However, in immunosuppressed patients, it may be found in unusual locations, as in the case of an intestinal condition. In some cases, this can be fatal. Small intestine CMV location is extremely rare.

CASE PRESENTATION: 40-year-old man with AIDS presenting secondary massive lower gastrointestinal bleeding (MLGB) symptoms and ulcer granulomatous injuries located in the proximal ileum produced by the association of CMV and histoplasmosis.

CONCLUSION: Lower gastrointestinal bleeding diagnosis and treatment pose a challenge, considering the intestine extension and difficulties for its exploration. On the other hand, the association between Histoplasmosis and CMV as a massive gastrointestinal bleeding cause has not been described. There is no bibliography on the matter.

Copyright © 2016. Published by Elsevier Ltd.

Keywords: AIDS; Case report; Cytomegalovirus; HIV; Histoplasmosis; Massive gastrointestinal bleeding

References

  1. Medicine (Baltimore). 1990 Nov;69(6):361-74 - PubMed
  2. J Pediatr Surg. 1990 Jun;25(6):696-8 - PubMed
  3. Clin Microbiol Rev. 2007 Jan;20(1):115-32 - PubMed
  4. J Clin Gastroenterol. 2000 Jun;30(4):432-5 - PubMed
  5. Natl Med J India. 2005 Mar-Apr;18(2):76-7 - PubMed
  6. Am Rev Respir Dis. 1990 Jun;141(6):1582-98 - PubMed
  7. Gastroenterol Clin Biol. 2005 Oct;29(10):1057-9 - PubMed
  8. Medicine (Baltimore). 1980 Jan;59(1):1-33 - PubMed
  9. J Clin Gastroenterol. 1992 Jan;14 (1):52-5 - PubMed

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