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Baek JO, Lee HY, Lee JR, et al. Acrokeratosis Paraneoplastica with Adenocarcinoma of the Colon Treated with Topical Tretinoin. Ann Dermatol. 2008;20(4):216-20doi: 10.5021/ad.2008.20.4.216.
Baek, J. O., Lee, H. Y., Lee, J. R., & Roh, J. Y. (2008). Acrokeratosis Paraneoplastica with Adenocarcinoma of the Colon Treated with Topical Tretinoin. Annals of dermatology, 20(4), 216-20. https://doi.org/10.5021/ad.2008.20.4.216
Baek, Jin Ok, et al. "Acrokeratosis Paraneoplastica with Adenocarcinoma of the Colon Treated with Topical Tretinoin." Annals of dermatology vol. 20,4 (2008): 216-20. doi: https://doi.org/10.5021/ad.2008.20.4.216
Baek JO, Lee HY, Lee JR, Roh JY. Acrokeratosis Paraneoplastica with Adenocarcinoma of the Colon Treated with Topical Tretinoin. Ann Dermatol. 2008 Dec;20(4):216-20. doi: 10.5021/ad.2008.20.4.216. Epub 2008 Dec 31. PMID: 27303196; PMCID: PMC4903983.
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Ann Dermatol. 2008 Dec;20(4):216-20. doi: 10.5021/ad.2008.20.4.216. Epub 2008 Dec 31.

Acrokeratosis Paraneoplastica with Adenocarcinoma of the Colon Treated with Topical Tretinoin.

Annals of dermatology

Jin Ok Baek, Hye Young Lee, Jong Rok Lee, Joo Young Roh

Affiliations

  1. Department of Dermatology, Gachon University of Medicine and Science, Incheon, Korea.

PMID: 27303196 PMCID: PMC4903983 DOI: 10.5021/ad.2008.20.4.216

Abstract

Acrokeratosis paraneoplastica, or Bazex syndrome, is one of the paraneoplastic syndromes. The characteristic skin lesions include palmoplantar keratoderma, psoriasiform skin lesions, hyperpigmentation, and nail dystrophy. The most common associated neoplasms are squamous cell carcinoma of the upper respiratory tract and other kinds of tumors with cervical lymph node metastasis. A 63-year-old woman presented with an 11 month history of hyperkeratotic lesions on the palms and soles. Ten months before she had been diagnosed with adenocarcinoma of the colon and undergone a left hemicolectomy. We report a case of acrokeratosis paraneoplastica associated with colon cancer which persisted after removal of the primary cancer, but resolved with topical tretinoin treatment.

Keywords: Acrokeratosis paraneoplastica; Bazex syndrome; Colon cancer; Tretinoin

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