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F1000Res. 2016 May 31;5. doi: 10.12688/f1000research.7693.1. eCollection 2016.

Recent advances in managing and understanding diabetic nephropathy.

F1000Research

Sydney C W Tang, Gary C W Chan, Kar Neng Lai

Affiliations

  1. Division of Nephrology, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.
  2. Division of Nephrology, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong; Nephrology Department, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong.

PMID: 27303648 PMCID: PMC4892357 DOI: 10.12688/f1000research.7693.1

Abstract

Diabetic nephropathy is the commonest cause of end-stage renal disease in most developed economies. Current standard of care for diabetic nephropathy embraces stringent blood pressure control via blockade of the renin-angiotensin-aldosterone system and glycemia control. Recent understanding of the pathophysiology of diabetic nephropathy has led to the development of novel therapeutic options. This review article focuses on available data from landmark studies on the main therapeutic approaches and highlights some novel management strategies.

Keywords: Diabetic nephropathy; glycemia control

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