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Case Rep Gastroenterol. 2016 May 19;10(1):30-5. doi: 10.1159/000442971. eCollection 2016.

Intestinal Anisakiasis Treated Successfully with Prednisolone and Olopatadine Hydrochloride.

Case reports in gastroenterology

Hideki Toyoda, Kyosuke Tanaka

Affiliations

  1. Happy GI Clinic, Kameyama, Japan.
  2. Department of Endoscopic Medicine, Mie University Hospital, Tsu, Japan.

PMID: 27403099 PMCID: PMC4929386 DOI: 10.1159/000442971

Abstract

The clinical characteristic of gastrointestinal anisakiasis is severe abdominal pain after eating raw fish. Intestinal anisakiasis is more uncommon than gastric anisakiasis. Most patients with intestinal anisakiasis need hospitalization because anisakiasis can cause intestinal obstruction, ileus, peritonitis or intestinal perforation. We report a case of intestinal anisakiasis. A 43-year-old woman presented with symptoms of intermittent abdominal pain 2 days after eating raw fish. Her brother had eaten the same food and had been suffering from gastric anisakiasis. Abdominal ultrasonography in this patient showed localized jejunal wall thickening with dilated lumen of proximal jejunum and ascites. According to the clinical course and examinations, she was diagnosed with intestinal anisakiasis. Administration of prednisolone 5 mg/day and olopatadine hydrochloride 10 mg/day improved her symptoms quickly without hospitalization. Prednisolone was administered for 10 days, and olopatadine hydrochloride was administered for a total of 6 weeks according to ultrasonographic findings. Six months after the treatment, the abdominal ultrasonography demonstrated normal findings. This case demonstrates that ultrasonography was quite useful for the diagnosis and surveillance of intestinal anisakiasis. Furthermore, treatment with corticosteroid and an antiallergic agent could be an option for patients with intestinal anisakiasis.

Keywords: Ambulatory care; Anisakis; Histamine antagonists; Prednisolone; Small intestine

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