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Case Rep Gastroenterol. 2016 May 09;10(1):168-73. doi: 10.1159/000443269. eCollection 2016.

A Case of Gastrointestinal Stromal Tumor That Underwent Endoscopic Ultrasound-Guided Aspiration with a 25-Gauge Biopsy Needle.

Case reports in gastroenterology

Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige

Affiliations

  1. Department of Gastroenterology, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Japan.
  2. Department of Radiology, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Japan.
  3. Department of Neurology, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Japan.
  4. Department of Rhuematology, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Japan.
  5. Department of Pediatrics, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Japan.
  6. Department of Neurosurgery, National Hospital Organization, Shimoshizu Hospital, Yotsukaido, Japan.

PMID: 27403121 PMCID: PMC4929380 DOI: 10.1159/000443269

Abstract

Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is performed to obtain specimens for pathological analysis. For this procedure, 19-gauge (19G), 22-guage (22G), and 25-guage (25G) needles are available. The needles are classified into aspiration type and biopsy type. A 56-year-old woman underwent upper gastrointestinal endoscopy that showed a 38-mm-diameter submucosal tumor. The elevated lesion was diagnosed as a submucosal tumor of the stomach. Contrast-enhanced computed tomography showed a low-density area on the luminal surface of the gastric wall, which was covered with a thin layer of gastric mucosa. EUS showed a hypoechoic lesion in the submucosal layer. Color Doppler image showed a pulsating vascular signal extending into the center of the hypoechoic lesion from the periphery. EUS-FNA was performed with a 25G biopsy needle. The specimen tissue consisted of spindle-shaped cells. The cells were positive for CD117 and CD34. The submucosal tumor was diagnosed as a gastrointestinal stromal tumor.

Keywords: CD117; CD34; Color Doppler; KIT; Ki-67; Submucosal tumor

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