Display options
Cite
Lee PH, Tu CT, Hsiao CC, et al. Antifibrotic Activity of Human Placental Amnion Membrane-Derived CD34+ Mesenchymal Stem/Progenitor Cell Transplantation in Mice With Thioacetamide-Induced Liver Injury. Stem Cells Transl Med. 2016;5(11):1473-1484doi: 10.5966/sctm.2015-0343.
Lee, P. H., Tu, C. T., Hsiao, C. C., Tsai, M. S., Ho, C. M., Cheng, N. C., Hung, T. M., & Shih, D. T. (2016). Antifibrotic Activity of Human Placental Amnion Membrane-Derived CD34+ Mesenchymal Stem/Progenitor Cell Transplantation in Mice With Thioacetamide-Induced Liver Injury. Stem cells translational medicine, 5(11), 1473-1484. https://doi.org/10.5966/sctm.2015-0343
Lee, Po-Huang, et al. "Antifibrotic Activity of Human Placental Amnion Membrane-Derived CD34+ Mesenchymal Stem/Progenitor Cell Transplantation in Mice With Thioacetamide-Induced Liver Injury." Stem cells translational medicine vol. 5,11 (2016): 1473-1484. doi: https://doi.org/10.5966/sctm.2015-0343
Lee PH, Tu CT, Hsiao CC, Tsai MS, Ho CM, Cheng NC, Hung TM, Shih DT. Antifibrotic Activity of Human Placental Amnion Membrane-Derived CD34+ Mesenchymal Stem/Progenitor Cell Transplantation in Mice With Thioacetamide-Induced Liver Injury. Stem Cells Transl Med. 2016 Nov;5(11):1473-1484. doi: 10.5966/sctm.2015-0343. Epub 2016 Jul 12. PMID: 27405780; PMCID: PMC5070504.
Copy Download .nbib Format: NLM
Share it on

Stem Cells Transl Med. 2016 Nov;5(11):1473-1484. doi: 10.5966/sctm.2015-0343. Epub 2016 Jul 12.

Antifibrotic Activity of Human Placental Amnion Membrane-Derived CD34+ Mesenchymal Stem/Progenitor Cell Transplantation in Mice With Thioacetamide-Induced Liver Injury.

Stem cells translational medicine

Po-Huang Lee, Chi-Tang Tu, Chih-Chiang Hsiao, Ming-Song Tsai, Cheng-Maw Ho, Nai-Chen Cheng, Tzu-Min Hung, Daniel Tzu-Bi Shih

Affiliations

  1. National Taiwan University Hospital, Taipei City, Taiwan, Republic of China.
  2. E-Da Hospital/I-Shou University, Yan-Chau Shiang, Kaohsiung County, Taiwan, Republic of China.
  3. Taipei Medical University Hospital, Taipei City, Taiwan, Republic of China.
  4. Prenatal Diagnosis Center, Cathay General Hospital, Taipei City, Taiwan, Republic of China.
  5. E-Da Hospital/I-Shou University, Yan-Chau Shiang, Kaohsiung County, Taiwan, Republic of China [email protected].
  6. Innovation Incubation Center, National Taiwan University Hospital, Taipei City, Taiwan, Republic of China.

PMID: 27405780 PMCID: PMC5070504 DOI: 10.5966/sctm.2015-0343

Abstract

: Liver fibrosis represents the end stage of chronic liver inflammatory diseases and is defined by the abnormal accumulation of extracellular matrix in the liver. Advanced liver fibrosis results in cirrhosis, liver failure, and portal hypertension. Liver transplantation has been the most effective treatment for these diseases, but the procedure is limited by the shortage of suitable donors. Mesenchymal stromal cells (MSCs) have shown great potential in the treatment of chronic inflammatory diseases associated with fibrosis. This study aimed to evaluate the therapeutic effect of MSC-based cell transplantation as an alternative treatment for liver fibrosis. A CD34-positive subpopulation of human placental amnion membrane-derived stem/progenitor cells (CD34

SIGNIFICANCE: In this study, a CD34

©AlphaMed Press.

Keywords: Antifibrotic; Human amnion membrane-derived CD34+ MSC; Thioacetamide-induced liver fibrosis; Transplantation

References

  1. Transplantation. 2005 Mar 15;79(5):528-35 - PubMed
  2. Curr Opin Gastroenterol. 2010 Jul;26(4):395-402 - PubMed
  3. Alcohol Clin Exp Res. 1989 Feb;13(1):15-9 - PubMed
  4. J Exp Med. 2007 Aug 6;204(8):1973-87 - PubMed
  5. J Surg Res. 2011 Jun 1;168(1):e51-9 - PubMed
  6. Mol Biol Cell. 2002 Dec;13(12):4279-95 - PubMed
  7. Am J Gastroenterol. 2008 Aug;103(8):1952-8 - PubMed
  8. Exp Biol Med (Maywood). 2014 Jan;239(1):105-15 - PubMed
  9. Cell J. 2012 Summer;14(2):142-51 - PubMed
  10. Biomaterials. 2012 Feb;33(6):1748-58 - PubMed
  11. Circ Res. 2010 May 28;106(10):1613-23 - PubMed
  12. Cell Transplant. 2010;19(11):1475-86 - PubMed
  13. Cell Stem Cell. 2008 Sep 11;3(3):301-13 - PubMed
  14. Hepatology. 2010 Jan;51(1):267-76 - PubMed
  15. Stem Cells. 2013 Oct;31(10):2231-41 - PubMed
  16. Ann Hematol. 2003 Oct;82(10):599-604 - PubMed
  17. Nature. 1981 Jul 9;292(5819):154-6 - PubMed
  18. Placenta. 2000 May;21(4):394-401 - PubMed
  19. World J Gastroenterol. 2007 Jun 28;13(24):3359-63 - PubMed
  20. PLoS One. 2014 Mar 19;9(3):e90883 - PubMed
  21. Annu Rev Pathol. 2011;6:457-78 - PubMed
  22. Cell. 2006 Aug 25;126(4):663-76 - PubMed
  23. Korean J Intern Med. 2015 Sep;30(5):580-9 - PubMed
  24. J Hepatol. 2007 Oct;47(4):598-607 - PubMed
  25. Gastroenterology. 2008 Aug;135(2):438-50 - PubMed
  26. Exp Cell Res. 2006 Apr 1;312(6):727-36 - PubMed
  27. Nature. 2011 Jun 29;475(7356):390-3 - PubMed
  28. Stem Cells. 2005 Mar;23 (3):412-23 - PubMed
  29. J Biol Chem. 2007 Jul 27;282(30):22089-101 - PubMed
  30. Cytotherapy. 2009;11(4):448-56 - PubMed
  31. Hepatology. 2007 Jan;45(1):213-22 - PubMed
  32. PLoS One. 2011 Feb 04;6(2):e16789 - PubMed
  33. Placenta. 2003 Feb-Mar;24(2-3):173-80 - PubMed
  34. Stem Cells. 2008 May;26(5):1307-14 - PubMed
  35. Biol Reprod. 1996 Dec;55(6):1253-60 - PubMed
  36. Differentiation. 2008 Feb;76(2):130-44 - PubMed
  37. Mech Ageing Dev. 2008 Mar;129(3):163-73 - PubMed
  38. Science. 1999 May 14;284(5417):1168-70 - PubMed
  39. Cytotherapy. 2003;5(5):362-9 - PubMed
  40. Circulation. 2003 Aug 19;108(7):863-8 - PubMed
  41. Stem Cells. 2009 Nov;27(11):2734-43 - PubMed
  42. J Hepatol. 2006 Apr;44(4):742-8 - PubMed
  43. Transplantation. 2013 Oct 27;96(8):697-706 - PubMed
  44. Stem Cells Cloning. 2011 Nov 17;4:61-72 - PubMed
  45. World J Gastroenterol. 2005 Jun 14;11(22):3431-40 - PubMed
  46. Bull Exp Biol Med. 2007 Oct;144(4):640-5 - PubMed
  47. Transplantation. 2004 Nov 27;78(10):1439-48 - PubMed
  48. ScientificWorldJournal. 2014;2014:103643 - PubMed
  49. Liver Transpl. 2009 May;15(5):484-95 - PubMed
  50. Hepatology. 2004 Dec;40(6):1304-11 - PubMed
  51. Hepatology. 2007 Jul;46(1):219-28 - PubMed
  52. Stem Cells. 2014 Jun;32(6):1380-9 - PubMed
  53. Cardiovasc Res. 2009 Aug 1;83(3):527-35 - PubMed
  54. Gut. 2009 Nov;58(11):1517-27 - PubMed
  55. Bone Marrow Transplant. 2005 May;35(10):1021-4 - PubMed

Publication Types